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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS54
All Species:
14.55
Human Site:
S720
Identified Species:
26.67
UniProt:
Q9P1Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1Q0
NP_001005739.1
977
110589
S720
I
A
L
P
E
K
K
S
G
A
T
E
E
R
K
Chimpanzee
Pan troglodytes
XP_001165146
977
110528
S720
I
A
L
P
E
K
K
S
G
A
T
E
E
R
K
Rhesus Macaque
Macaca mulatta
XP_001087667
977
110603
S720
I
A
L
P
E
K
K
S
G
T
T
E
E
R
K
Dog
Lupus familis
XP_531846
977
110860
S720
I
A
L
P
E
K
K
S
G
A
T
E
E
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5SPW0
977
110378
P720
I
A
L
P
E
K
K
P
V
V
T
E
E
R
K
Rat
Rattus norvegicus
Q9JMK8
965
108823
P708
I
A
L
P
D
K
K
P
A
A
T
E
D
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511329
978
110848
P721
I
T
L
P
E
K
K
P
G
T
S
E
E
R
K
Chicken
Gallus gallus
XP_419349
979
111040
P722
I
S
L
P
E
K
K
P
T
G
T
E
E
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124248
998
112046
H740
I
S
L
P
E
R
K
H
S
S
G
S
E
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLC0
940
105223
N691
Y
A
K
P
E
M
G
N
L
I
S
N
G
A
G
Honey Bee
Apis mellifera
XP_001121762
883
100031
L649
E
L
K
T
K
L
T
L
L
L
E
S
E
R
W
Nematode Worm
Caenorhab. elegans
Q22639
1058
119163
S803
E
S
A
V
T
I
D
S
T
T
S
T
S
N
Q
Sea Urchin
Strong. purpuratus
XP_790678
943
106615
G688
N
S
S
P
L
M
Y
G
A
S
R
E
R
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
96.5
N.A.
92.6
89.9
N.A.
90.8
86.5
N.A.
67.3
N.A.
24.1
36.5
21
48.8
Protein Similarity:
100
99.9
99.6
98
N.A.
96.3
94.2
N.A.
94.6
93.5
N.A.
81.8
N.A.
42.5
54.1
42.2
67
P-Site Identity:
100
100
93.3
100
N.A.
80
73.3
N.A.
73.3
73.3
N.A.
40
N.A.
20
13.3
6.6
13.3
P-Site Similarity:
100
100
93.3
100
N.A.
80
86.6
N.A.
80
80
N.A.
66.6
N.A.
33.3
20
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
8
0
0
0
0
0
16
31
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
0
0
8
8
0
% D
% Glu:
16
0
0
0
70
0
0
0
0
0
8
70
70
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
39
8
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
70
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
16
0
8
62
70
0
0
0
0
0
0
8
62
% K
% Leu:
0
8
70
0
8
8
0
8
16
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
85
0
0
0
31
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
8
0
8
70
8
% R
% Ser:
0
31
8
0
0
0
0
39
8
16
24
16
8
0
0
% S
% Thr:
0
8
0
8
8
0
8
0
16
24
54
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _