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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS54
All Species:
32.73
Human Site:
T588
Identified Species:
60
UniProt:
Q9P1Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1Q0
NP_001005739.1
977
110589
T588
V
S
E
D
M
K
L
T
D
S
E
L
G
K
L
Chimpanzee
Pan troglodytes
XP_001165146
977
110528
T588
V
S
E
D
M
K
L
T
D
S
E
L
G
K
L
Rhesus Macaque
Macaca mulatta
XP_001087667
977
110603
T588
V
S
E
D
M
K
L
T
D
S
E
L
G
K
L
Dog
Lupus familis
XP_531846
977
110860
T588
V
N
E
D
M
K
L
T
D
L
E
L
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SPW0
977
110378
T588
V
S
E
D
M
R
L
T
D
L
E
L
G
K
L
Rat
Rattus norvegicus
Q9JMK8
965
108823
T576
V
S
E
D
M
R
L
T
D
L
E
L
G
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511329
978
110848
T589
F
S
E
D
V
K
L
T
D
L
E
L
G
K
L
Chicken
Gallus gallus
XP_419349
979
111040
T590
I
S
D
D
M
K
L
T
E
L
E
L
G
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124248
998
112046
S608
A
L
E
D
V
M
P
S
D
L
E
L
G
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLC0
940
105223
F559
N
L
I
D
S
E
A
F
L
S
P
G
H
H
E
Honey Bee
Apis mellifera
XP_001121762
883
100031
A525
R
D
T
V
D
L
A
A
G
R
V
C
D
G
S
Nematode Worm
Caenorhab. elegans
Q22639
1058
119163
A679
S
R
L
L
I
A
R
A
K
N
A
S
V
T
E
Sea Urchin
Strong. purpuratus
XP_790678
943
106615
A556
P
Q
G
D
F
L
I
A
P
N
E
H
Q
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
96.5
N.A.
92.6
89.9
N.A.
90.8
86.5
N.A.
67.3
N.A.
24.1
36.5
21
48.8
Protein Similarity:
100
99.9
99.6
98
N.A.
96.3
94.2
N.A.
94.6
93.5
N.A.
81.8
N.A.
42.5
54.1
42.2
67
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
80
66.6
N.A.
40
N.A.
13.3
0
0
20
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
66.6
N.A.
20
0
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
16
24
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
8
85
8
0
0
0
62
0
0
0
8
0
0
% D
% Glu:
0
0
62
0
0
8
0
0
8
0
77
0
8
0
16
% E
% Phe:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
8
0
0
8
62
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% H
% Ile:
8
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
47
0
0
8
0
0
0
0
54
0
% K
% Leu:
0
16
8
8
0
16
62
0
8
47
0
70
0
0
70
% L
% Met:
0
0
0
0
54
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
8
8
0
0
0
16
8
0
0
8
0
0
0
24
0
% R
% Ser:
8
54
0
0
8
0
0
8
0
31
0
8
0
0
8
% S
% Thr:
0
0
8
0
0
0
0
62
0
0
0
0
0
8
0
% T
% Val:
47
0
0
8
16
0
0
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _