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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR3B All Species: 58.18
Human Site: Y100 Identified Species: 80
UniProt: Q9P1U1 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1U1 NP_065178.1 418 47608 Y100 M E Q V V F K Y L R A E P E D
Chimpanzee Pan troglodytes XP_001143822 413 46798 Y100 M E Q V V F K Y L R A E P E D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532772 528 60166 Y210 M E Q V I F K Y L R A E P E D
Cat Felis silvestris
Mouse Mus musculus Q641P0 418 47561 Y100 M E Q V V F K Y L R A E P E D
Rat Rattus norvegicus P68035 377 42000 G76 L K Y P I E H G I I T N W D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513007 482 55165 Y164 M E Q V I F K Y L R A E P E D
Chicken Gallus gallus Q90WD0 418 47403 Y100 M E Q V I F K Y L R A E P E D
Frog Xenopus laevis P10995 377 41970 G76 L K Y P I E H G I I T N W D D
Zebra Danio Brachydanio rerio NP_001003944 418 47376 Y100 M E Q V I F K Y L R A E P E D
Tiger Blowfish Takifugu rubipres O73723 418 47447 Y100 M E Q I I F K Y L R A E P E D
Fruit Fly Dros. melanogaster P32392 418 47014 Y100 L E Q C V F K Y L R A E P E D
Honey Bee Apis mellifera XP_393599 417 46840 Y100 L Q Q C I F K Y L R A E P E D
Nematode Worm Caenorhab. elegans Q9N4I0 425 48069 Y107 W E Q C I F K Y L R A E P E D
Sea Urchin Strong. purpuratus XP_780265 418 47124 Y100 L E Q S I F K Y L R A E P E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SAF1 427 47641 Y112 W Q Q C I F N Y L R C D P E D
Baker's Yeast Sacchar. cerevisiae P47117 449 49523 Y138 W E N S I F K Y L R T E P E D
Red Bread Mold Neurospora crassa P78712 439 47833 Y125 W S N S I F K Y L R V E P E D
Conservation
Percent
Protein Identity: 100 93.5 N.A. 78 N.A. 98.5 37.3 N.A. 84.6 91.1 37.5 89.4 89.2 79.6 76 72.7 81.3
Protein Similarity: 100 94.9 N.A. 78.7 N.A. 100 53.1 N.A. 85.8 96.6 53.1 95.9 95.6 89.4 88.7 84 91.1
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 6.6 N.A. 93.3 93.3 6.6 93.3 86.6 86.6 73.3 80 80
P-Site Similarity: 100 100 N.A. 100 N.A. 100 40 N.A. 100 100 40 100 100 93.3 93.3 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 59.2 58.5 59.2
Protein Similarity: N.A. N.A. N.A. 74.9 70.3 72.4
P-Site Identity: N.A. N.A. N.A. 53.3 66.6 60
P-Site Similarity: N.A. N.A. N.A. 73.3 73.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 71 0 0 0 0 % A
% Cys: 0 0 0 24 0 0 0 0 0 0 6 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 6 0 12 100 % D
% Glu: 0 71 0 0 0 12 0 0 0 0 0 83 0 89 0 % E
% Phe: 0 0 0 0 0 89 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 6 77 0 0 0 12 12 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 83 0 0 0 0 0 0 0 0 % K
% Leu: 30 0 0 0 0 0 0 0 89 0 0 0 0 0 0 % L
% Met: 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 6 0 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 0 0 0 0 89 0 0 % P
% Gln: 0 12 77 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 89 0 0 0 0 0 % R
% Ser: 0 6 0 18 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 % T
% Val: 0 0 0 42 24 0 0 0 0 0 6 0 0 0 0 % V
% Trp: 24 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % W
% Tyr: 0 0 12 0 0 0 0 89 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _