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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR3B All Species: 45.76
Human Site: Y245 Identified Species: 62.92
UniProt: Q9P1U1 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1U1 NP_065178.1 418 47608 Y245 I V K E F A K Y D V D P R K W
Chimpanzee Pan troglodytes XP_001143822 413 46798 Y245 I V K E F A K Y D V D P R K W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532772 528 60166 Y355 I V K E F A K Y D V D P R K W
Cat Felis silvestris
Mouse Mus musculus Q641P0 418 47561 Y245 I V R E F A K Y D V D P R K W
Rat Rattus norvegicus P68035 377 42000 V221 I K E K L C Y V A L D F E N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513007 482 55165 Y309 I V K E F A K Y D V D P R K W
Chicken Gallus gallus Q90WD0 418 47403 Y245 L V K E F N K Y D T D G T K W
Frog Xenopus laevis P10995 377 41970 V221 I K E K L C Y V A L D F E N E
Zebra Danio Brachydanio rerio NP_001003944 418 47376 Y245 L V K E F S K Y D T D G S K W
Tiger Blowfish Takifugu rubipres O73723 418 47447 Y245 L V K E F N K Y D T D G S K W
Fruit Fly Dros. melanogaster P32392 418 47014 Y245 I A K E F A K Y D T E P G K W
Honey Bee Apis mellifera XP_393599 417 46840 Y245 I S K E F A K Y D S D P T K I
Nematode Worm Caenorhab. elegans Q9N4I0 425 48069 Y252 V M K E F V K Y D T D A A K W
Sea Urchin Strong. purpuratus XP_780265 418 47124 Y245 I A K E F T K Y D T D P S K W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SAF1 427 47641 H254 I V K E F N K H D K E P A K Y
Baker's Yeast Sacchar. cerevisiae P47117 449 49523 F280 I V K E F N K F D K D P S K F
Red Bread Mold Neurospora crassa P78712 439 47833 Y267 I V K E F A K Y D R D R S R F
Conservation
Percent
Protein Identity: 100 93.5 N.A. 78 N.A. 98.5 37.3 N.A. 84.6 91.1 37.5 89.4 89.2 79.6 76 72.7 81.3
Protein Similarity: 100 94.9 N.A. 78.7 N.A. 100 53.1 N.A. 85.8 96.6 53.1 95.9 95.6 89.4 88.7 84 91.1
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 13.3 N.A. 100 66.6 13.3 66.6 66.6 73.3 73.3 60 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 33.3 N.A. 100 73.3 33.3 80 73.3 80 73.3 73.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 59.2 58.5 59.2
Protein Similarity: N.A. N.A. N.A. 74.9 70.3 72.4
P-Site Identity: N.A. N.A. N.A. 60 66.6 66.6
P-Site Similarity: N.A. N.A. N.A. 80 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 48 0 0 12 0 0 6 12 0 0 % A
% Cys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 89 0 89 0 0 0 0 % D
% Glu: 0 0 12 89 0 0 0 0 0 0 12 0 12 0 12 % E
% Phe: 0 0 0 0 89 0 0 6 0 0 0 12 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 18 6 0 0 % G
% His: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 77 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % I
% Lys: 0 12 83 12 0 0 89 0 0 12 0 0 0 83 0 % K
% Leu: 18 0 0 0 12 0 0 0 0 12 0 0 0 0 0 % L
% Met: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 24 0 0 0 0 0 0 0 12 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 6 0 0 0 0 0 0 6 0 6 30 6 0 % R
% Ser: 0 6 0 0 0 6 0 0 0 6 0 0 30 0 0 % S
% Thr: 0 0 0 0 0 6 0 0 0 36 0 0 12 0 0 % T
% Val: 6 65 0 0 0 6 0 12 0 30 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 % W
% Tyr: 0 0 0 0 0 0 12 77 0 0 0 0 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _