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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR3B
All Species:
33.03
Human Site:
Y403
Identified Species:
45.42
UniProt:
Q9P1U1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1U1
NP_065178.1
418
47608
Y403
T
K
K
D
Y
E
E
Y
G
P
S
I
C
R
H
Chimpanzee
Pan troglodytes
XP_001143822
413
46798
P398
S
L
E
G
S
V
S
P
F
L
C
S
R
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532772
528
60166
Y513
T
K
K
D
Y
E
E
Y
G
P
S
I
C
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q641P0
418
47561
Y403
T
K
K
D
Y
E
E
Y
G
P
S
I
C
R
H
Rat
Rattus norvegicus
P68035
377
42000
Q362
Q
Q
M
W
I
S
K
Q
E
Y
D
E
A
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513007
482
55165
Y467
T
K
K
D
Y
E
E
Y
G
P
S
I
C
R
H
Chicken
Gallus gallus
Q90WD0
418
47403
I403
T
K
K
D
Y
E
E
I
G
P
S
I
C
R
H
Frog
Xenopus laevis
P10995
377
41970
Q362
Q
Q
M
W
I
T
K
Q
E
Y
D
E
A
G
P
Zebra Danio
Brachydanio rerio
NP_001003944
418
47376
I403
T
K
K
D
Y
E
E
I
G
P
S
I
C
R
H
Tiger Blowfish
Takifugu rubipres
O73723
418
47447
I403
T
K
K
D
Y
E
E
I
G
P
S
I
C
R
H
Fruit Fly
Dros. melanogaster
P32392
418
47014
Y403
T
K
A
A
Y
E
E
Y
G
P
S
I
C
R
H
Honey Bee
Apis mellifera
XP_393599
417
46840
Y402
T
K
K
A
Y
Q
E
Y
G
P
G
I
C
R
Y
Nematode Worm
Caenorhab. elegans
Q9N4I0
425
48069
R410
T
K
A
E
Y
M
E
R
G
P
S
I
C
R
Y
Sea Urchin
Strong. purpuratus
XP_780265
418
47124
I403
T
K
S
D
Y
D
E
I
G
P
S
I
C
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAF1
427
47641
Y412
T
K
E
E
Y
E
E
Y
G
A
S
I
C
R
T
Baker's Yeast
Sacchar. cerevisiae
P47117
449
49523
Y435
T
K
K
D
Y
E
E
Y
G
P
E
I
V
R
N
Red Bread Mold
Neurospora crassa
P78712
439
47833
Y422
T
K
A
E
Y
Q
E
Y
G
P
S
I
V
R
R
Conservation
Percent
Protein Identity:
100
93.5
N.A.
78
N.A.
98.5
37.3
N.A.
84.6
91.1
37.5
89.4
89.2
79.6
76
72.7
81.3
Protein Similarity:
100
94.9
N.A.
78.7
N.A.
100
53.1
N.A.
85.8
96.6
53.1
95.9
95.6
89.4
88.7
84
91.1
P-Site Identity:
100
0
N.A.
100
N.A.
100
0
N.A.
100
93.3
0
93.3
93.3
86.6
73.3
66.6
80
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
13.3
N.A.
100
93.3
13.3
93.3
93.3
86.6
86.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
59.2
58.5
59.2
Protein Similarity:
N.A.
N.A.
N.A.
74.9
70.3
72.4
P-Site Identity:
N.A.
N.A.
N.A.
73.3
80
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
86.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
18
12
0
0
0
0
0
6
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
0
71
0
0
% C
% Asp:
0
0
0
53
0
6
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
12
18
0
59
83
0
12
0
6
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
0
0
83
0
6
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
53
% H
% Ile:
0
0
0
0
12
0
0
24
0
0
0
83
0
0
0
% I
% Lys:
0
83
53
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
6
0
0
0
0
0
0
0
6
0
0
0
6
0
% L
% Met:
0
0
12
0
0
6
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% N
% Pro:
0
0
0
0
0
0
0
6
0
77
0
0
0
0
12
% P
% Gln:
12
12
0
0
0
12
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
6
0
0
0
0
6
83
6
% R
% Ser:
6
0
6
0
6
6
6
0
0
0
71
6
0
0
6
% S
% Thr:
83
0
0
0
0
6
0
0
0
0
0
0
0
0
6
% T
% Val:
0
0
0
0
0
6
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
83
0
0
53
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _