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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63C
All Species:
6.67
Human Site:
S215
Identified Species:
14.67
UniProt:
Q9P1W3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1W3
NP_065164.2
806
93317
S215
L
G
F
A
P
R
N
S
Q
K
V
T
R
T
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
E276
Q
S
I
K
Y
K
E
E
N
L
V
R
R
T
L
Dog
Lupus familis
XP_547926
804
93648
S214
L
G
F
V
P
K
R
S
Y
R
V
T
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBX0
802
92993
S213
L
G
F
V
P
K
K
S
L
H
F
T
R
T
L
Rat
Rattus norvegicus
NP_001101515
802
92944
N213
L
G
F
V
P
K
K
N
L
H
F
T
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
E225
Q
S
I
K
Y
K
E
E
S
L
V
R
R
T
L
Chicken
Gallus gallus
XP_421286
830
95065
N234
I
H
L
E
Y
R
E
N
E
K
V
A
R
T
L
Frog
Xenopus laevis
NP_001088752
803
91863
E225
S
A
I
K
Y
K
E
E
N
M
V
K
Q
T
L
Zebra Danio
Brachydanio rerio
NP_001153308
796
91478
D227
S
R
L
E
Y
R
E
D
E
K
V
A
R
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
F215
G
G
Y
I
M
R
H
F
L
K
K
V
R
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
K185
N
I
P
N
K
D
A
K
L
W
V
H
T
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
35.7
84.9
N.A.
83.6
82.8
N.A.
41.9
57.3
44.1
52.9
N.A.
N.A.
32.7
N.A.
35.7
Protein Similarity:
100
N.A.
54.1
93.3
N.A.
91.8
91.8
N.A.
62.9
75.1
62.6
73.3
N.A.
N.A.
52.3
N.A.
55.5
P-Site Identity:
100
N.A.
26.6
66.6
N.A.
60
53.3
N.A.
26.6
40
20
40
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
N.A.
33.3
80
N.A.
66.6
66.6
N.A.
33.3
60
33.3
46.6
N.A.
N.A.
40
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
10
0
0
0
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
19
0
0
46
28
19
0
0
0
0
0
0
% E
% Phe:
0
0
37
0
0
0
0
10
0
0
19
0
0
0
10
% F
% Gly:
10
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
10
0
0
19
0
10
0
0
0
% H
% Ile:
10
10
28
10
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
28
10
55
19
10
0
37
10
10
0
0
0
% K
% Leu:
37
0
19
0
0
0
0
0
37
19
0
0
0
0
82
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
10
19
19
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
37
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
10
0
0
0
37
10
0
0
10
0
19
82
0
0
% R
% Ser:
19
19
0
0
0
0
0
28
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
37
10
82
0
% T
% Val:
0
0
0
28
0
0
0
0
0
0
73
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
10
0
46
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _