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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM63C All Species: 12.12
Human Site: S577 Identified Species: 26.67
UniProt: Q9P1W3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1W3 NP_065164.2 806 93317 S577 Y S T R L F F S R S E P E R V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089796 853 97098 A636 Y T F R M I M A K T A A D R R
Dog Lupus familis XP_547926 804 93648 S576 Y S I R L F F S R S E P E R V
Cat Felis silvestris
Mouse Mus musculus Q8CBX0 802 92993 S575 Y C T R L F L S K S E P E R V
Rat Rattus norvegicus NP_001101515 802 92944 S575 Y C T R L F L S R S E P E R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512688 801 91795 V588 I L Y T I R M V T A K T A A D
Chicken Gallus gallus XP_421286 830 95065 A595 Y T A R L C L A K S E P E R L
Frog Xenopus laevis NP_001088752 803 91863 A591 Y T I R M I M A K S A G E R R
Zebra Danio Brachydanio rerio NP_001153308 796 91478 V580 L R I P A L L V Y S L R L C F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392828 767 85105 F553 S G L E L V R F P E L A L Y T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785977 734 83832 V522 F E Y S L K S V A E I K M R W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 35.7 84.9 N.A. 83.6 82.8 N.A. 41.9 57.3 44.1 52.9 N.A. N.A. 32.7 N.A. 35.7
Protein Similarity: 100 N.A. 54.1 93.3 N.A. 91.8 91.8 N.A. 62.9 75.1 62.6 73.3 N.A. N.A. 52.3 N.A. 55.5
P-Site Identity: 100 N.A. 20 93.3 N.A. 80 86.6 N.A. 0 53.3 33.3 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 N.A. 60 93.3 N.A. 86.6 86.6 N.A. 20 80 60 6.6 N.A. N.A. 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 0 28 10 10 19 19 10 10 0 % A
% Cys: 0 19 0 0 0 10 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 0 10 0 10 0 0 0 0 0 19 46 0 55 0 0 % E
% Phe: 10 0 10 0 0 37 19 10 0 0 0 0 0 0 10 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 28 0 10 19 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 37 0 10 10 0 0 0 % K
% Leu: 10 10 10 0 64 10 37 0 0 0 19 0 19 0 10 % L
% Met: 0 0 0 0 19 0 28 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 10 0 0 46 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 64 0 10 10 0 28 0 0 10 0 73 19 % R
% Ser: 10 19 0 10 0 0 10 37 0 64 0 0 0 0 0 % S
% Thr: 0 28 28 10 0 0 0 0 10 10 0 10 0 0 10 % T
% Val: 0 0 0 0 0 10 0 28 0 0 0 0 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 64 0 19 0 0 0 0 0 10 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _