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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM63C All Species: 14.55
Human Site: S77 Identified Species: 32
UniProt: Q9P1W3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1W3 NP_065164.2 806 93317 S77 A L L I H N D S L T S L I Y G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089796 853 97098 L136 W D Y G R I A L V S E A D S E
Dog Lupus familis XP_547926 804 93648 S76 A L L I H N D S L T S L I Y G
Cat Felis silvestris
Mouse Mus musculus Q8CBX0 802 92993 L76 L L I H N D S L T S L I Y G E
Rat Rattus norvegicus NP_001101515 802 92944 L76 L L I H N D S L T S L I Y G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512688 801 91795 S91 A L V S E A E S E S S Y Q R L
Chicken Gallus gallus XP_421286 830 95065 S93 A L L M D N D S L T S L F Y G
Frog Xenopus laevis NP_001088752 803 91863 V86 D Y G R V A L V Y D A D S S P
Zebra Danio Brachydanio rerio NP_001153308 796 91478 S90 A L L M K N D S L T S L F Y G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392828 767 85105 E80 A L L N K T D E R W V E L F Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785977 734 83832 R51 V V L F A I F R K V A G D Y G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 35.7 84.9 N.A. 83.6 82.8 N.A. 41.9 57.3 44.1 52.9 N.A. N.A. 32.7 N.A. 35.7
Protein Similarity: 100 N.A. 54.1 93.3 N.A. 91.8 91.8 N.A. 62.9 75.1 62.6 73.3 N.A. N.A. 52.3 N.A. 55.5
P-Site Identity: 100 N.A. 0 100 N.A. 6.6 6.6 N.A. 26.6 80 0 80 N.A. N.A. 26.6 N.A. 20
P-Site Similarity: 100 N.A. 13.3 100 N.A. 40 40 N.A. 46.6 86.6 6.6 86.6 N.A. N.A. 40 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 0 0 0 10 19 10 0 0 0 19 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 10 19 46 0 0 10 0 10 19 0 0 % D
% Glu: 0 0 0 0 10 0 10 10 10 0 10 10 0 0 28 % E
% Phe: 0 0 0 10 0 0 10 0 0 0 0 0 19 10 0 % F
% Gly: 0 0 10 10 0 0 0 0 0 0 0 10 0 19 46 % G
% His: 0 0 0 19 19 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 19 19 0 19 0 0 0 0 0 19 19 0 0 % I
% Lys: 0 0 0 0 19 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 19 73 55 0 0 0 10 28 37 0 19 37 10 0 10 % L
% Met: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 19 37 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 10 0 0 10 10 0 0 0 0 10 0 % R
% Ser: 0 0 0 10 0 0 19 46 0 37 46 0 10 19 0 % S
% Thr: 0 0 0 0 0 10 0 0 19 37 0 0 0 0 0 % T
% Val: 10 10 10 0 10 0 0 10 10 10 10 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 0 0 0 10 0 0 10 19 46 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _