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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63C
All Species:
8.18
Human Site:
S91
Identified Species:
18
UniProt:
Q9P1W3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1W3
NP_065164.2
806
93317
S91
G
E
Q
S
E
K
T
S
P
S
E
T
S
L
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
S150
E
S
R
F
Q
R
L
S
S
T
S
S
S
G
Q
Dog
Lupus familis
XP_547926
804
93648
S90
G
E
Q
S
E
K
T
S
P
S
D
I
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBX0
802
92993
P90
E
Q
S
E
K
S
S
P
S
E
V
S
L
E
A
Rat
Rattus norvegicus
NP_001101515
802
92944
P90
E
Q
S
E
K
S
S
P
S
E
V
Y
L
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
S105
L
S
S
S
S
S
S
S
H
L
D
F
E
S
D
Chicken
Gallus gallus
XP_421286
830
95065
K107
G
E
Q
S
E
K
E
K
S
P
S
E
S
S
P
Frog
Xenopus laevis
NP_001088752
803
91863
L100
P
H
S
R
Y
R
R
L
S
S
S
S
S
S
E
Zebra Danio
Brachydanio rerio
NP_001153308
796
91478
K104
G
E
Q
S
E
K
E
K
T
P
S
D
S
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
D94
Y
G
D
N
E
G
R
D
T
E
A
I
C
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
Q65
G
R
I
A
L
V
N
Q
G
E
E
R
W
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
35.7
84.9
N.A.
83.6
82.8
N.A.
41.9
57.3
44.1
52.9
N.A.
N.A.
32.7
N.A.
35.7
Protein Similarity:
100
N.A.
54.1
93.3
N.A.
91.8
91.8
N.A.
62.9
75.1
62.6
73.3
N.A.
N.A.
52.3
N.A.
55.5
P-Site Identity:
100
N.A.
13.3
86.6
N.A.
0
0
N.A.
13.3
46.6
20
46.6
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
53.3
93.3
N.A.
26.6
20
N.A.
33.3
46.6
33.3
46.6
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
19
10
0
0
10
% D
% Glu:
28
37
0
19
46
0
19
0
0
37
19
10
10
19
37
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
46
10
0
0
0
10
0
0
10
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
19
0
10
0
% I
% Lys:
0
0
0
0
19
37
0
19
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
10
0
10
10
0
10
0
0
19
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
19
19
19
0
0
0
0
19
% P
% Gln:
0
19
37
0
10
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
10
10
10
0
19
19
0
0
0
0
10
0
0
0
% R
% Ser:
0
19
37
46
10
28
28
37
46
28
37
28
55
37
10
% S
% Thr:
0
0
0
0
0
0
19
0
19
10
0
10
0
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _