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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63C
All Species:
24.55
Human Site:
Y245
Identified Species:
54
UniProt:
Q9P1W3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1W3
NP_065164.2
806
93317
Y245
I
K
H
F
H
E
A
Y
P
G
S
V
V
T
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
Y305
E
S
H
F
R
D
A
Y
P
T
C
E
V
V
D
Dog
Lupus familis
XP_547926
804
93648
Y244
I
K
H
F
H
E
A
Y
P
G
C
V
V
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBX0
802
92993
Y243
S
K
H
F
H
E
A
Y
P
G
C
V
V
T
R
Rat
Rattus norvegicus
NP_001101515
802
92944
Y243
S
K
H
F
H
E
A
Y
P
G
C
V
V
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
Y254
E
N
H
F
R
D
A
Y
P
T
C
R
V
V
E
Chicken
Gallus gallus
XP_421286
830
95065
Y264
I
K
H
F
H
E
A
Y
P
S
C
T
V
T
N
Frog
Xenopus laevis
NP_001088752
803
91863
Y254
D
L
H
F
S
E
A
Y
P
S
C
Q
V
E
E
Zebra Danio
Brachydanio rerio
NP_001153308
796
91478
Y257
T
K
H
L
H
E
A
Y
P
S
C
T
V
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
H241
L
I
T
E
I
P
K
H
Q
C
N
V
Q
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
L211
M
R
H
F
S
M
H
L
P
Y
R
S
E
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
35.7
84.9
N.A.
83.6
82.8
N.A.
41.9
57.3
44.1
52.9
N.A.
N.A.
32.7
N.A.
35.7
Protein Similarity:
100
N.A.
54.1
93.3
N.A.
91.8
91.8
N.A.
62.9
75.1
62.6
73.3
N.A.
N.A.
52.3
N.A.
55.5
P-Site Identity:
100
N.A.
40
93.3
N.A.
86.6
86.6
N.A.
40
73.3
46.6
60
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
N.A.
46.6
93.3
N.A.
86.6
86.6
N.A.
46.6
73.3
46.6
60
N.A.
N.A.
33.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
82
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
73
0
0
0
0
% C
% Asp:
10
0
0
0
0
19
0
0
0
0
0
0
0
0
28
% D
% Glu:
19
0
0
10
0
64
0
0
0
0
0
10
10
10
19
% E
% Phe:
0
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
37
0
0
0
0
0
% G
% His:
0
0
91
0
55
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
28
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
55
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
10
0
0
0
10
0
0
0
0
0
0
10
% L
% Met:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
91
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% Q
% Arg:
0
10
0
0
19
0
0
0
0
0
10
10
0
0
37
% R
% Ser:
19
10
0
0
19
0
0
0
0
28
10
10
0
10
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
19
0
19
0
64
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
46
82
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _