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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM63C All Species: 17.27
Human Site: Y637 Identified Species: 38
UniProt: Q9P1W3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1W3 NP_065164.2 806 93317 Y637 M K H L T D R Y N M Y Y S F A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089796 853 97098 M692 I Y I L L K H M V D R H N L Y
Dog Lupus familis XP_547926 804 93648 Y636 M K H I T D R Y N M Y Y S Y A
Cat Felis silvestris
Mouse Mus musculus Q8CBX0 802 92993 Y635 M K H I T D R Y N M Y Y S Y A
Rat Rattus norvegicus NP_001101515 802 92944 Y635 M K H I T D R Y N M Y Y S Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512688 801 91795 L642 P F G L I Y I L L K H M V D R
Chicken Gallus gallus XP_421286 830 95065 Y655 L K H M V D R Y N I Y Y V Y I
Frog Xenopus laevis NP_001088752 803 91863 K645 G L I Y L L L K H M V D R H N
Zebra Danio Brachydanio rerio NP_001153308 796 91478 G635 C P V I V P F G L L Y L V L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392828 767 85105 P607 T V Y S L A C P L I T P F G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785977 734 83832 E576 N M L W T R S E A E K I T K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 35.7 84.9 N.A. 83.6 82.8 N.A. 41.9 57.3 44.1 52.9 N.A. N.A. 32.7 N.A. 35.7
Protein Similarity: 100 N.A. 54.1 93.3 N.A. 91.8 91.8 N.A. 62.9 75.1 62.6 73.3 N.A. N.A. 52.3 N.A. 55.5
P-Site Identity: 100 N.A. 6.6 86.6 N.A. 86.6 86.6 N.A. 6.6 53.3 6.6 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 N.A. 26.6 100 N.A. 100 100 N.A. 13.3 80 13.3 20 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 37 % A
% Cys: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 46 0 0 0 10 0 10 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 10 0 0 0 0 0 10 10 0 % F
% Gly: 10 0 10 0 0 0 0 10 0 0 0 0 0 10 0 % G
% His: 0 0 46 0 0 0 10 0 10 0 10 10 0 10 0 % H
% Ile: 10 0 19 37 10 0 10 0 0 19 0 10 0 0 10 % I
% Lys: 0 46 0 0 0 10 0 10 0 10 10 0 0 10 10 % K
% Leu: 10 10 10 28 28 10 10 10 28 10 0 10 0 19 10 % L
% Met: 37 10 0 10 0 0 0 10 0 46 0 10 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 46 0 0 0 10 0 10 % N
% Pro: 10 10 0 0 0 10 0 10 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 46 0 0 0 10 0 10 0 19 % R
% Ser: 0 0 0 10 0 0 10 0 0 0 0 0 37 0 0 % S
% Thr: 10 0 0 0 46 0 0 0 0 0 10 0 10 0 0 % T
% Val: 0 10 10 0 19 0 0 0 10 0 10 0 28 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 10 0 10 0 46 0 0 55 46 0 37 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _