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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63C
All Species:
18.48
Human Site:
Y640
Identified Species:
40.67
UniProt:
Q9P1W3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1W3
NP_065164.2
806
93317
Y640
L
T
D
R
Y
N
M
Y
Y
S
F
A
P
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
R695
L
L
K
H
M
V
D
R
H
N
L
Y
F
V
Y
Dog
Lupus familis
XP_547926
804
93648
Y639
I
T
D
R
Y
N
M
Y
Y
S
Y
A
P
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBX0
802
92993
Y638
I
T
D
R
Y
N
M
Y
Y
S
Y
A
P
T
K
Rat
Rattus norvegicus
NP_001101515
802
92944
Y638
I
T
D
R
Y
N
M
Y
Y
S
Y
A
P
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
H645
L
I
Y
I
L
L
K
H
M
V
D
R
H
N
L
Chicken
Gallus gallus
XP_421286
830
95065
Y658
M
V
D
R
Y
N
I
Y
Y
V
Y
I
P
T
K
Frog
Xenopus laevis
NP_001088752
803
91863
V648
Y
L
L
L
K
H
M
V
D
R
H
N
L
Y
Y
Zebra Danio
Brachydanio rerio
NP_001153308
796
91478
Y638
I
V
P
F
G
L
L
Y
L
V
L
K
H
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
T610
S
L
A
C
P
L
I
T
P
F
G
L
L
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
K579
W
T
R
S
E
A
E
K
I
T
K
R
S
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
35.7
84.9
N.A.
83.6
82.8
N.A.
41.9
57.3
44.1
52.9
N.A.
N.A.
32.7
N.A.
35.7
Protein Similarity:
100
N.A.
54.1
93.3
N.A.
91.8
91.8
N.A.
62.9
75.1
62.6
73.3
N.A.
N.A.
52.3
N.A.
55.5
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
86.6
86.6
N.A.
6.6
60
6.6
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
13.3
80
13.3
20
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
0
0
37
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
46
0
0
0
10
0
10
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
10
0
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
10
0
10
0
10
10
0
10
0
19
0
0
% H
% Ile:
37
10
0
10
0
0
19
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
10
0
10
10
0
0
10
10
0
0
46
% K
% Leu:
28
28
10
10
10
28
10
0
10
0
19
10
19
0
19
% L
% Met:
10
0
0
0
10
0
46
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
46
0
0
0
10
0
10
0
10
0
% N
% Pro:
0
0
10
0
10
0
0
0
10
0
0
0
46
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
46
0
0
0
10
0
10
0
19
0
0
0
% R
% Ser:
10
0
0
10
0
0
0
0
0
37
0
0
10
0
10
% S
% Thr:
0
46
0
0
0
0
0
10
0
10
0
0
0
46
0
% T
% Val:
0
19
0
0
0
10
0
10
0
28
0
0
0
19
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
46
0
0
55
46
0
37
10
0
19
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _