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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1543 All Species: 5.45
Human Site: S588 Identified Species: 13.33
UniProt: Q9P1Y5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1Y5 NP_065953.1 1249 134750 S588 A G A G S P T S T P A P P E A
Chimpanzee Pan troglodytes XP_001143924 1462 165093 Q722 P E E T G L P Q G R D T T Q L
Rhesus Macaque Macaca mulatta XP_001090322 1105 118834 G516 A E P G S V P G G E R P A G E
Dog Lupus familis XP_542112 1161 125823 A537 A E A G S P A A T P T A P E A
Cat Felis silvestris
Mouse Mus musculus Q80VC9 1252 135157 S589 S G L G S P T S T P V A P E A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512372 1107 119674 K516 T S F A E R K K H L L K P E G
Chicken Gallus gallus XP_415410 1602 178816 P865 R E Q S P S R P N K D N V N L
Frog Xenopus laevis Q6IRN6 1576 175916 Q849 R E Q S P G R Q N R D H A N V
Zebra Danio Brachydanio rerio A5WUN7 1558 173882 S685 A F R P L V T S S V E P S S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAU8 1630 183603 E569 S T S G Y D P E S T P V R K S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.8 86.7 75.5 N.A. 90.5 N.A. N.A. 64 29.1 29.7 29.3 N.A. 21 N.A. N.A. N.A.
Protein Similarity: 100 49.5 86.9 78.5 N.A. 93.2 N.A. N.A. 69.8 44.1 45.2 43.6 N.A. 35.6 N.A. N.A. N.A.
P-Site Identity: 100 0 26.6 66.6 N.A. 73.3 N.A. N.A. 13.3 0 0 33.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 26.6 73.3 N.A. 80 N.A. N.A. 13.3 0 0 40 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 20 10 0 0 10 10 0 0 10 20 20 0 40 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 30 0 0 0 0 % D
% Glu: 0 50 10 0 10 0 0 10 0 10 10 0 0 40 10 % E
% Phe: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 20 0 50 10 10 0 10 20 0 0 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 10 0 10 0 10 0 10 0 % K
% Leu: 0 0 10 0 10 10 0 0 0 10 10 0 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 20 0 0 10 0 20 0 % N
% Pro: 10 0 10 10 20 30 30 10 0 30 10 30 40 0 0 % P
% Gln: 0 0 20 0 0 0 0 20 0 0 0 0 0 10 0 % Q
% Arg: 20 0 10 0 0 10 20 0 0 20 10 0 10 0 0 % R
% Ser: 20 10 10 20 40 10 0 30 20 0 0 0 10 10 10 % S
% Thr: 10 10 0 10 0 0 30 0 30 10 10 10 10 0 0 % T
% Val: 0 0 0 0 0 20 0 0 0 10 10 10 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _