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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALCOCO1 All Species: 13.64
Human Site: S539 Identified Species: 33.33
UniProt: Q9P1Z2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1Z2 NP_001137154.1 691 77336 S539 C P A A L T D S E D E S P E D
Chimpanzee Pan troglodytes XP_509103 926 103504 P599 V G L S P C S P N L E A E D E
Rhesus Macaque Macaca mulatta XP_001107806 690 77273 S538 C P A A L T D S E D E S P E D
Dog Lupus familis XP_543631 690 76837 D538 S C P E A L T D S E D E S P E
Cat Felis silvestris
Mouse Mus musculus Q8CGU1 691 77262 S539 C P A S L T D S E D E S P E D
Rat Rattus norvegicus Q66HR5 691 77257 S539 C P A A L T D S E D E S P E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510062 824 94531 G670 R Q P V L H F G N P Y G P Q E
Chicken Gallus gallus XP_418731 816 93694 G662 R L P V L Q Y G N P Y A I Q E
Frog Xenopus laevis Q6DD09 547 63016 Q397 R S Q R Q A L Q C K L N Q E T
Zebra Danio Brachydanio rerio A2BGD5 640 73406 E488 E K E Q L Q T E I Q E V M E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63 98.2 91.7 N.A. 89.2 89.1 N.A. 28 29 37.7 32.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 66.3 98.5 94.7 N.A. 92.9 93.3 N.A. 48 49.5 56 52.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 0 N.A. 93.3 100 N.A. 13.3 6.6 6.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 20 N.A. 100 100 N.A. 26.6 26.6 13.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 40 30 10 10 0 0 0 0 0 20 0 0 0 % A
% Cys: 40 10 0 0 0 10 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 40 10 0 40 10 0 0 10 40 % D
% Glu: 10 0 10 10 0 0 0 10 40 10 60 10 10 60 40 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 20 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 10 10 0 70 10 10 0 0 10 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 30 0 0 10 0 0 0 % N
% Pro: 0 40 30 0 10 0 0 10 0 20 0 0 50 10 0 % P
% Gln: 0 10 10 10 10 20 0 10 0 10 0 0 10 20 0 % Q
% Arg: 30 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 0 20 0 0 10 40 10 0 0 40 10 0 0 % S
% Thr: 0 0 0 0 0 40 20 0 0 0 0 0 0 0 10 % T
% Val: 10 0 0 20 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 20 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _