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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM5
All Species:
18.48
Human Site:
S350
Identified Species:
40.67
UniProt:
Q9P217
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P217
NP_065934.1
1185
130634
S350
E
Q
V
K
L
F
L
S
Q
G
G
Y
C
G
S
Chimpanzee
Pan troglodytes
XP_513126
1395
153015
S560
E
Q
V
K
L
F
L
S
Q
G
G
Y
C
G
S
Rhesus Macaque
Macaca mulatta
XP_001094447
1002
112341
M208
T
L
I
T
E
Q
F
M
A
D
P
R
L
T
L
Dog
Lupus familis
XP_853236
1229
135332
S394
E
Q
V
K
L
F
L
S
Q
G
G
Y
Y
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80TC6
1188
130908
S353
E
Q
V
K
L
F
L
S
Q
G
G
Y
Y
G
S
Rat
Rattus norvegicus
NP_001101433
911
102414
M117
T
L
I
T
E
Q
F
M
A
D
P
R
L
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507506
824
90485
G29
Q
L
L
P
G
I
P
G
G
A
H
R
L
G
A
Chicken
Gallus gallus
XP_422431
1110
122366
M316
T
L
I
T
E
Q
F
M
A
D
P
R
L
S
L
Frog
Xenopus laevis
NP_001090431
1092
121735
P298
T
E
Q
F
L
E
D
P
R
L
A
L
W
R
Q
Zebra Danio
Brachydanio rerio
NP_001138291
1151
128439
S318
E
Q
V
K
Q
F
L
S
Q
G
G
Y
Y
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
T189
A
R
M
L
T
L
I
T
E
Q
F
M
V
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
83.6
84.5
N.A.
95.7
74.3
N.A.
42.7
78.6
61.4
82.1
N.A.
N.A.
N.A.
N.A.
52.5
Protein Similarity:
100
84.8
84.3
86.8
N.A.
97.3
75.7
N.A.
50.1
84.8
74.8
88
N.A.
N.A.
N.A.
N.A.
63.5
P-Site Identity:
100
100
0
93.3
N.A.
93.3
0
N.A.
6.6
0
6.6
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
6.6
93.3
N.A.
93.3
6.6
N.A.
26.6
6.6
20
86.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
28
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
28
0
0
0
10
0
% D
% Glu:
46
10
0
0
28
10
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
46
28
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
10
46
46
0
0
55
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
28
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
37
10
10
46
10
46
0
0
10
0
10
37
0
28
% L
% Met:
0
0
10
0
0
0
0
28
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
10
0
0
28
0
0
0
10
% P
% Gln:
10
46
10
0
10
28
0
0
46
10
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
0
0
0
10
0
0
37
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
46
0
0
0
0
0
10
46
% S
% Thr:
37
0
0
28
10
0
0
10
0
0
0
0
0
19
0
% T
% Val:
0
0
46
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
46
28
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _