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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZSWIM5 All Species: 19.39
Human Site: S377 Identified Species: 42.67
UniProt: Q9P217 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P217 NP_065934.1 1185 130634 S377 E M L R M R D S N G A R M L T
Chimpanzee Pan troglodytes XP_513126 1395 153015 S587 E M L R M R D S N G A R M L T
Rhesus Macaque Macaca mulatta XP_001094447 1002 112341 G235 R Q L W D E L G A L W V C I I
Dog Lupus familis XP_853236 1229 135332 S421 E M L R M R D S N G A R M L T
Cat Felis silvestris
Mouse Mus musculus Q80TC6 1188 130908 S380 E M L R M R D S N G A R M L T
Rat Rattus norvegicus NP_001101433 911 102414 G144 R Q L W D E L G A L W V C I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507506 824 90485 T56 A V P A E P Q T V C N V A I S
Chicken Gallus gallus XP_422431 1110 122366 G343 R Q L W D E L G A L W V C V V
Frog Xenopus laevis NP_001090431 1092 121735 W325 W D E L G A L W V C V V L S P
Zebra Danio Brachydanio rerio NP_001138291 1151 128439 S345 E M L R M R D S N G A R M L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789113 983 110838 W216 T D K H R Q L W D Q L G L L W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 83.6 84.5 N.A. 95.7 74.3 N.A. 42.7 78.6 61.4 82.1 N.A. N.A. N.A. N.A. 52.5
Protein Similarity: 100 84.8 84.3 86.8 N.A. 97.3 75.7 N.A. 50.1 84.8 74.8 88 N.A. N.A. N.A. N.A. 63.5
P-Site Identity: 100 100 6.6 100 N.A. 100 6.6 N.A. 0 6.6 0 100 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 13.3 N.A. 26.6 13.3 6.6 100 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 10 0 0 28 0 46 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 19 0 0 28 0 0 % C
% Asp: 0 19 0 0 28 0 46 0 10 0 0 0 0 0 0 % D
% Glu: 46 0 10 0 10 28 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 28 0 46 0 10 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 19 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 73 10 0 0 46 0 0 28 10 0 19 55 0 % L
% Met: 0 46 0 0 46 0 0 0 0 0 0 0 46 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 46 0 10 0 0 0 0 % N
% Pro: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 28 0 0 0 10 10 0 0 10 0 0 0 0 0 % Q
% Arg: 28 0 0 46 10 46 0 0 0 0 0 46 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 46 0 0 0 0 0 10 10 % S
% Thr: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 46 % T
% Val: 0 10 0 0 0 0 0 0 19 0 10 46 0 10 10 % V
% Trp: 10 0 0 28 0 0 0 19 0 0 28 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _