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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZSWIM5 All Species: 9.09
Human Site: S522 Identified Species: 20
UniProt: Q9P217 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P217 NP_065934.1 1185 130634 S522 A P A C Q R E S E R L L F N S
Chimpanzee Pan troglodytes XP_513126 1395 153015 S732 A P A C Q R E S E R L L F N S
Rhesus Macaque Macaca mulatta XP_001094447 1002 112341 L366 A C A R V D A L R S H G Y P K
Dog Lupus familis XP_853236 1229 135332 S566 A P A C Q Q E S E R L L F N S
Cat Felis silvestris
Mouse Mus musculus Q80TC6 1188 130908 N525 A P A C Q R E N E R L L F N S
Rat Rattus norvegicus NP_001101433 911 102414 L275 A C A R V D A L R S H G Y P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507506 824 90485 L188 Q E Q V K L F L S Q G G Y H G
Chicken Gallus gallus XP_422431 1110 122366 L474 A C A R V D A L R S H G Y P R
Frog Xenopus laevis NP_001090431 1092 121735 G456 V D A L R S H G Y P Q Q A L R
Zebra Danio Brachydanio rerio NP_001138291 1151 128439 G489 S P A Y Q R E G E S L L F N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789113 983 110838 V347 L P T A C A R V D A L R S H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 83.6 84.5 N.A. 95.7 74.3 N.A. 42.7 78.6 61.4 82.1 N.A. N.A. N.A. N.A. 52.5
Protein Similarity: 100 84.8 84.3 86.8 N.A. 97.3 75.7 N.A. 50.1 84.8 74.8 88 N.A. N.A. N.A. N.A. 63.5
P-Site Identity: 100 100 13.3 93.3 N.A. 93.3 13.3 N.A. 0 13.3 6.6 66.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 20 100 N.A. 100 20 N.A. 26.6 20 13.3 73.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 64 0 82 10 0 10 28 0 0 10 0 0 10 0 0 % A
% Cys: 0 28 0 37 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 28 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 46 0 46 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 46 0 0 % F
% Gly: 0 0 0 0 0 0 0 19 0 0 10 37 0 0 19 % G
% His: 0 0 0 0 0 0 10 0 0 0 28 0 0 19 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 19 % K
% Leu: 10 0 0 10 0 10 0 37 0 0 55 46 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 46 0 % N
% Pro: 0 55 0 0 0 0 0 0 0 10 0 0 0 28 10 % P
% Gln: 10 0 10 0 46 10 0 0 0 10 10 10 0 0 0 % Q
% Arg: 0 0 0 28 10 37 10 0 28 37 0 10 0 0 19 % R
% Ser: 10 0 0 0 0 10 0 28 10 37 0 0 10 0 37 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 10 28 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 10 0 0 0 37 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _