KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM5
All Species:
9.09
Human Site:
S64
Identified Species:
20
UniProt:
Q9P217
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P217
NP_065934.1
1185
130634
S64
R
P
H
L
Q
P
D
S
L
L
D
C
A
A
K
Chimpanzee
Pan troglodytes
XP_513126
1395
153015
S274
R
P
H
L
Q
P
E
S
L
L
D
C
A
A
K
Rhesus Macaque
Macaca mulatta
XP_001094447
1002
112341
Dog
Lupus familis
XP_853236
1229
135332
R78
Q
S
S
P
P
P
G
R
A
A
V
S
Q
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80TC6
1188
130908
S64
R
P
H
L
Q
P
E
S
L
L
D
C
A
A
K
Rat
Rattus norvegicus
NP_001101433
911
102414
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507506
824
90485
Chicken
Gallus gallus
XP_422431
1110
122366
P59
G
A
G
G
S
G
A
P
A
A
S
A
G
C
C
Frog
Xenopus laevis
NP_001090431
1092
121735
R42
A
F
E
Q
V
E
E
R
F
S
R
V
P
E
P
Zebra Danio
Brachydanio rerio
NP_001138291
1151
128439
K59
S
L
L
D
C
A
A
K
A
V
A
E
K
W
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
83.6
84.5
N.A.
95.7
74.3
N.A.
42.7
78.6
61.4
82.1
N.A.
N.A.
N.A.
N.A.
52.5
Protein Similarity:
100
84.8
84.3
86.8
N.A.
97.3
75.7
N.A.
50.1
84.8
74.8
88
N.A.
N.A.
N.A.
N.A.
63.5
P-Site Identity:
100
93.3
0
6.6
N.A.
93.3
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
0
13.3
N.A.
100
0
N.A.
0
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
19
0
28
19
10
10
28
28
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
28
0
10
10
% C
% Asp:
0
0
0
10
0
0
10
0
0
0
28
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
28
0
0
0
0
10
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% F
% Gly:
10
0
10
10
0
10
10
0
0
0
0
0
10
0
0
% G
% His:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
28
% K
% Leu:
0
10
10
28
0
0
0
0
28
28
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
28
0
10
10
37
0
10
0
0
0
0
10
0
19
% P
% Gln:
10
0
0
10
28
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
28
0
0
0
0
0
0
19
0
0
10
0
0
0
0
% R
% Ser:
10
10
10
0
10
0
0
28
0
10
10
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
10
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _