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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZSWIM5 All Species: 18.48
Human Site: T489 Identified Species: 40.67
UniProt: Q9P217 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P217 NP_065934.1 1185 130634 T489 R P R R T V F T R A I E G R E
Chimpanzee Pan troglodytes XP_513126 1395 153015 T699 R P R R T V F T R A I E G R E
Rhesus Macaque Macaca mulatta XP_001094447 1002 112341 P333 S S D V Y T A P A C Q R E S E
Dog Lupus familis XP_853236 1229 135332 T533 R P R R T V F T R A I E G R E
Cat Felis silvestris
Mouse Mus musculus Q80TC6 1188 130908 T492 R P R R T V F T R A I E G R E
Rat Rattus norvegicus NP_001101433 911 102414 P242 S S D I Y T A P A C Q R E N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507506 824 90485 V155 Q N S E I N Q V H G A P D P T
Chicken Gallus gallus XP_422431 1110 122366 P441 S S D F Y V S P A Y Q R E G E
Frog Xenopus laevis NP_001090431 1092 121735 S423 P S S A V K S S T D M L S Y D
Zebra Danio Brachydanio rerio NP_001138291 1151 128439 T456 R P R R T V F T R A M E A C D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789113 983 110838 F314 N V L N K D Y F M C V H H I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 83.6 84.5 N.A. 95.7 74.3 N.A. 42.7 78.6 61.4 82.1 N.A. N.A. N.A. N.A. 52.5
Protein Similarity: 100 84.8 84.3 86.8 N.A. 97.3 75.7 N.A. 50.1 84.8 74.8 88 N.A. N.A. N.A. N.A. 63.5
P-Site Identity: 100 100 6.6 100 N.A. 100 6.6 N.A. 0 13.3 0 73.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 6.6 100 N.A. 100 6.6 N.A. 6.6 13.3 20 86.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 19 0 28 46 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 28 0 0 0 10 0 % C
% Asp: 0 0 28 0 0 10 0 0 0 10 0 0 10 0 19 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 46 28 0 64 % E
% Phe: 0 0 0 10 0 0 46 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 37 10 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 10 10 0 0 % H
% Ile: 0 0 0 10 10 0 0 0 0 0 37 0 0 10 0 % I
% Lys: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 19 0 0 0 0 % M
% Asn: 10 10 0 10 0 10 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 46 0 0 0 0 0 28 0 0 0 10 0 10 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 0 28 0 0 0 0 % Q
% Arg: 46 0 46 46 0 0 0 0 46 0 0 28 0 37 0 % R
% Ser: 28 37 19 0 0 0 19 10 0 0 0 0 10 10 0 % S
% Thr: 0 0 0 0 46 19 0 46 10 0 0 0 0 0 10 % T
% Val: 0 10 0 10 10 55 0 10 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 28 0 10 0 0 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _