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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZSWIM5
All Species:
18.18
Human Site:
Y554
Identified Species:
40
UniProt:
Q9P217
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.6
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P217
NP_065934.1
1185
130634
Y554
D
A
L
R
S
H
G
Y
P
K
E
A
L
R
L
Chimpanzee
Pan troglodytes
XP_513126
1395
153015
Y764
D
A
L
R
S
H
G
Y
P
K
E
A
L
R
L
Rhesus Macaque
Macaca mulatta
XP_001094447
1002
112341
K398
Q
R
Q
L
E
I
Y
K
H
Q
K
K
E
L
L
Dog
Lupus familis
XP_853236
1229
135332
Y598
D
A
L
R
S
H
G
Y
P
K
E
A
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80TC6
1188
130908
Y557
D
A
L
R
S
H
G
Y
P
K
E
A
L
R
L
Rat
Rattus norvegicus
NP_001101433
911
102414
K307
Q
R
Q
L
E
I
Y
K
H
Q
K
K
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507506
824
90485
R220
M
R
D
S
N
G
A
R
M
L
T
L
I
T
E
Chicken
Gallus gallus
XP_422431
1110
122366
K506
Q
R
Q
L
E
I
Y
K
H
Q
K
K
E
L
L
Frog
Xenopus laevis
NP_001090431
1092
121735
K488
E
S
V
K
Q
Q
R
K
E
L
Q
L
K
G
I
Zebra Danio
Brachydanio rerio
NP_001138291
1151
128439
Y521
D
A
L
R
S
H
G
Y
P
R
E
A
L
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789113
983
110838
K379
K
V
Q
Q
D
H
L
K
Q
A
K
H
S
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
83.6
84.5
N.A.
95.7
74.3
N.A.
42.7
78.6
61.4
82.1
N.A.
N.A.
N.A.
N.A.
52.5
Protein Similarity:
100
84.8
84.3
86.8
N.A.
97.3
75.7
N.A.
50.1
84.8
74.8
88
N.A.
N.A.
N.A.
N.A.
63.5
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
0
6.6
0
93.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
13.3
20
40
100
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
0
0
10
0
0
10
0
46
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
28
0
0
0
10
0
46
0
28
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
46
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
55
0
0
28
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
28
0
0
0
0
0
0
10
0
10
% I
% Lys:
10
0
0
10
0
0
0
46
0
37
37
28
10
10
0
% K
% Leu:
0
0
46
28
0
0
10
0
0
19
0
19
46
28
73
% L
% Met:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% P
% Gln:
28
0
37
10
10
10
0
0
10
28
10
0
0
0
0
% Q
% Arg:
0
37
0
46
0
0
10
10
0
10
0
0
0
46
0
% R
% Ser:
0
10
0
10
46
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
28
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _