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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZSWIM5 All Species: 17.58
Human Site: Y627 Identified Species: 38.67
UniProt: Q9P217 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P217 NP_065934.1 1185 130634 Y627 C R L N D D G Y L E M S D M N
Chimpanzee Pan troglodytes XP_513126 1395 153015 Y837 C R L N D D G Y L E M S D M N
Rhesus Macaque Macaca mulatta XP_001094447 1002 112341 S467 H V P M A A G S P N S S E S Y
Dog Lupus familis XP_853236 1229 135332 Y671 C R L N D D G Y L E V S D M N
Cat Felis silvestris
Mouse Mus musculus Q80TC6 1188 130908 Y630 C R L N D D S Y M E M S D M N
Rat Rattus norvegicus NP_001101433 911 102414 C376 H V P V A S G C P S S N E S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507506 824 90485 V289 K Q W N S V D V C P W E D G N
Chicken Gallus gallus XP_422431 1110 122366 S575 H V P V T T G S Q D S G E S Y
Frog Xenopus laevis NP_001090431 1092 121735 G557 L P G A T A N G E S Y L C L A
Zebra Danio Brachydanio rerio NP_001138291 1151 128439 T594 C R V E D D N T M D T G D S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789113 983 110838 N448 H V R V T G S N D P L E S Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 83.6 84.5 N.A. 95.7 74.3 N.A. 42.7 78.6 61.4 82.1 N.A. N.A. N.A. N.A. 52.5
Protein Similarity: 100 84.8 84.3 86.8 N.A. 97.3 75.7 N.A. 50.1 84.8 74.8 88 N.A. N.A. N.A. N.A. 63.5
P-Site Identity: 100 100 13.3 93.3 N.A. 86.6 6.6 N.A. 20 6.6 0 33.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 20 100 N.A. 93.3 20 N.A. 26.6 20 6.6 53.3 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 19 19 0 0 0 0 0 0 0 0 10 % A
% Cys: 46 0 0 0 0 0 0 10 10 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 46 46 10 0 10 19 0 0 55 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 10 37 0 19 28 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 10 55 10 0 0 0 19 0 10 10 % G
% His: 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 37 0 0 0 0 0 28 0 10 10 0 10 10 % L
% Met: 0 0 0 10 0 0 0 0 19 0 28 0 0 37 0 % M
% Asn: 0 0 0 46 0 0 19 10 0 10 0 10 0 0 46 % N
% Pro: 0 10 28 0 0 0 0 0 19 19 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 46 10 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 10 19 19 0 19 28 46 10 37 0 % S
% Thr: 0 0 0 0 28 10 0 10 0 0 10 0 0 0 0 % T
% Val: 0 37 10 28 0 10 0 10 0 0 10 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 37 0 0 10 0 0 10 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _