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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC88C All Species: 16.97
Human Site: S452 Identified Species: 46.67
UniProt: Q9P219 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P219 NP_001073883.2 2028 228214 S452 L S D A S R K S F V F E L N E
Chimpanzee Pan troglodytes XP_510123 2028 228228 S452 L S D A S R K S F V F E L N E
Rhesus Macaque Macaca mulatta XP_001089462 721 76195
Dog Lupus familis XP_537539 2361 264711 S382 L S D A S R K S F V F E L N E
Cat Felis silvestris
Mouse Mus musculus Q6VGS5 2009 226516 S452 L S D A S R K S F V F E L N E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514444 1718 196022 A375 E Q L T A A R A R G D K V H E
Chicken Gallus gallus
Frog Xenopus laevis P85120 2058 236320 S451 D L S D A R K S F V F E L N E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397453 1177 136326
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782798 1863 213363 A431 A K L N T S A A T S L S A E C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 32 63 N.A. 82.3 N.A. N.A. 63.3 N.A. 55.2 N.A. N.A. N.A. 24 N.A. 33.9
Protein Similarity: 100 99.7 33 68.6 N.A. 88.6 N.A. N.A. 72.9 N.A. 71.5 N.A. N.A. N.A. 39.3 N.A. 54.9
P-Site Identity: 100 100 0 100 N.A. 100 N.A. N.A. 6.6 N.A. 66.6 N.A. N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 0 100 N.A. 100 N.A. N.A. 46.6 N.A. 73.3 N.A. N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 45 23 12 12 23 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % C
% Asp: 12 0 45 12 0 0 0 0 0 0 12 0 0 0 0 % D
% Glu: 12 0 0 0 0 0 0 0 0 0 0 56 0 12 67 % E
% Phe: 0 0 0 0 0 0 0 0 56 0 56 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 0 0 0 0 56 0 0 0 0 12 0 0 0 % K
% Leu: 45 12 23 0 0 0 0 0 0 0 12 0 56 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 12 0 0 0 0 0 0 0 0 0 56 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 56 12 0 12 0 0 0 0 0 0 % R
% Ser: 0 45 12 0 45 12 0 56 0 12 0 12 0 0 0 % S
% Thr: 0 0 0 12 12 0 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 56 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _