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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP23 All Species: 10.91
Human Site: S423 Identified Species: 34.29
UniProt: Q9P227 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P227 NP_065927 1491 162192 S423 Y I G Y R S Y S P S F Q R R T
Chimpanzee Pan troglodytes XP_507699 1957 217438 S566 V A P S V V N S D N R Q M S G
Rhesus Macaque Macaca mulatta XP_001082710 1794 194113 S726 Y I G Y R S Y S P S F Q R R T
Dog Lupus familis XP_548158 1061 116725 H95 G G P S P R H H R L E P M D T
Cat Felis silvestris
Mouse Mus musculus Q69ZH9 1483 161813 S421 Y I G Y R S Y S P S F Q R R T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506140 1948 216249 S571 H P D G R R I S G R G V G S M
Chicken Gallus gallus
Frog Xenopus laevis Q71M21 1902 211444 A590 N F Q N S S R A P H P R P A L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391884 1943 218848 N524 N L S G H R T N S G T S S T S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.4 80 66.4 N.A. 92.2 N.A. N.A. 34 N.A. 34.7 N.A. N.A. N.A. 23 N.A. N.A.
Protein Similarity: 100 45.7 80.9 67.7 N.A. 94.3 N.A. N.A. 46.6 N.A. 48 N.A. N.A. N.A. 37 N.A. N.A.
P-Site Identity: 100 13.3 100 6.6 N.A. 100 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 20 100 13.3 N.A. 100 N.A. N.A. 20 N.A. 26.6 N.A. N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 13 0 0 0 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 0 0 0 0 13 0 0 0 0 13 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % E
% Phe: 0 13 0 0 0 0 0 0 0 0 38 0 0 0 0 % F
% Gly: 13 13 38 25 0 0 0 0 13 13 13 0 13 0 13 % G
% His: 13 0 0 0 13 0 13 13 0 13 0 0 0 0 0 % H
% Ile: 0 38 0 0 0 0 13 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 13 0 0 0 0 0 0 0 13 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 13 % M
% Asn: 25 0 0 13 0 0 13 13 0 13 0 0 0 0 0 % N
% Pro: 0 13 25 0 13 0 0 0 50 0 13 13 13 0 0 % P
% Gln: 0 0 13 0 0 0 0 0 0 0 0 50 0 0 0 % Q
% Arg: 0 0 0 0 50 38 13 0 13 13 13 13 38 38 0 % R
% Ser: 0 0 13 25 13 50 0 63 13 38 0 13 13 25 13 % S
% Thr: 0 0 0 0 0 0 13 0 0 0 13 0 0 13 50 % T
% Val: 13 0 0 0 13 13 0 0 0 0 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 38 0 0 38 0 0 38 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _