Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP23 All Species: 11.82
Human Site: T1252 Identified Species: 37.14
UniProt: Q9P227 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P227 NP_065927 1491 162192 T1252 S I V S G Y S T L S T M D R S
Chimpanzee Pan troglodytes XP_507699 1957 217438 S1636 G R P V E T D S E S E F P V F
Rhesus Macaque Macaca mulatta XP_001082710 1794 194113 T1555 S I V S G Y S T L S T M D R S
Dog Lupus familis XP_548158 1061 116725 V847 V A A C C R I V E A R G L E S
Cat Felis silvestris
Mouse Mus musculus Q69ZH9 1483 161813 T1243 S I V S G Y S T L S T M D R S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506140 1948 216249 S1621 G R P V E T D S E S E F S I F
Chicken Gallus gallus
Frog Xenopus laevis Q71M21 1902 211444 E1585 V S E G R P M E T D S E N D F
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391884 1943 218848 S1710 R S T V S S T S E S S R L S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.4 80 66.4 N.A. 92.2 N.A. N.A. 34 N.A. 34.7 N.A. N.A. N.A. 23 N.A. N.A.
Protein Similarity: 100 45.7 80.9 67.7 N.A. 94.3 N.A. N.A. 46.6 N.A. 48 N.A. N.A. N.A. 37 N.A. N.A.
P-Site Identity: 100 6.6 100 6.6 N.A. 100 N.A. N.A. 6.6 N.A. 0 N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 13.3 100 13.3 N.A. 100 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 13 0 0 0 0 0 0 13 0 0 0 0 0 % A
% Cys: 0 0 0 13 13 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 25 0 0 13 0 0 38 13 0 % D
% Glu: 0 0 13 0 25 0 0 13 50 0 25 13 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 38 % F
% Gly: 25 0 0 13 38 0 0 0 0 0 0 13 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 38 0 0 0 0 13 0 0 0 0 0 0 13 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 38 0 0 0 25 0 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 0 38 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % N
% Pro: 0 0 25 0 0 13 0 0 0 0 0 0 13 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 13 25 0 0 13 13 0 0 0 0 13 13 0 38 0 % R
% Ser: 38 25 0 38 13 13 38 38 0 75 25 0 13 13 63 % S
% Thr: 0 0 13 0 0 25 13 38 13 0 38 0 0 0 0 % T
% Val: 25 0 38 38 0 0 0 13 0 0 0 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _