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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STIM2 All Species: 25.15
Human Site: S678 Identified Species: 61.48
UniProt: Q9P246 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P246 NP_065911.2 746 83971 S678 Y N G I L E K S C S M N Q L S
Chimpanzee Pan troglodytes XP_001166908 833 92979 S765 Y N G I L E K S C S M N Q L S
Rhesus Macaque Macaca mulatta XP_001084785 832 93014 S764 Y N G I L E K S C S M N Q L S
Dog Lupus familis XP_536267 621 69757 C554 N G I L E K S C S M N Q L S S
Cat Felis silvestris
Mouse Mus musculus P83093 746 83906 S678 Y N G I L E K S C S M H Q L S
Rat Rattus norvegicus P84903 685 77431 S618 L D S S H S H S P S S P D P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514272 738 83612 S670 Y N G I L E K S C S M N Q L S
Chicken Gallus gallus XP_420749 740 83061 S672 Y N G I L E K S C S M N Q L S
Frog Xenopus laevis NP_001090506 668 75433 S601 S H S D S S R S H S P S S T E
Zebra Danio Brachydanio rerio XP_692356 686 77932 E619 V A Y N G I L E K S Y S M G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.5 88.6 66.2 N.A. 93.5 46.3 N.A. 86 83.1 46.3 56 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 89.5 88.8 70.3 N.A. 96.3 60.8 N.A. 89.6 89.2 59.5 68.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 13.3 N.A. 100 100 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 20 N.A. 100 100 33.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 60 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 0 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 0 10 60 0 10 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 60 0 10 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 10 0 0 10 0 10 0 10 0 0 10 0 0 0 % H
% Ile: 0 0 10 60 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 60 0 10 0 0 0 0 0 0 % K
% Leu: 10 0 0 10 60 0 10 0 0 0 0 0 10 60 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 60 0 10 0 0 % M
% Asn: 10 60 0 10 0 0 0 0 0 0 10 50 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 10 10 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 60 0 10 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 20 10 10 20 10 80 10 90 10 20 10 10 70 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 60 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _