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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS18 All Species: 30
Human Site: S30 Identified Species: 50.77
UniProt: Q9P253 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P253 NP_065908.1 973 110186 S30 P S V G I P H S G Y V N A Q L
Chimpanzee Pan troglodytes XP_523187 973 110161 S30 P S V G I P H S G Y V N A Q L
Rhesus Macaque Macaca mulatta XP_001099146 973 110096 S30 P S V G I P H S G Y V N A Q L
Dog Lupus familis XP_544627 1095 122945 S152 P S V G I P H S G Y V N A Q L
Cat Felis silvestris
Mouse Mus musculus Q8R307 973 110200 S30 P S V G I P H S G Y V S A H L
Rat Rattus norvegicus NP_001099969 973 110167 S30 P S V G I P H S G Y V N A H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506026 612 69591
Chicken Gallus gallus XP_421131 974 112556 S30 A S V G I P H S G Y V N A R L
Frog Xenopus laevis NP_001085645 968 111576 G30 N P D I P L S G Y V N A R L E
Zebra Danio Brachydanio rerio P59015 974 113248 S30 A N I G I T H S G F V N V R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24314 1002 115316 A31 A N S Y V A T A S G N P F E T
Honey Bee Apis mellifera XP_396968 718 83450
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172709 994 113061 G30 M I T C M A A G N D V I V L G
Baker's Yeast Sacchar. cerevisiae P27801 918 107380 L30 L K V S N D Q L I V T T Q R T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.6 86.6 N.A. 95.7 95.1 N.A. 52.8 74 68.3 65.9 N.A. 34.7 34.6 N.A. N.A.
Protein Similarity: 100 99.9 99.9 87.4 N.A. 97.5 97.1 N.A. 56.4 86.4 83.2 82.4 N.A. 53.6 51.4 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 0 86.6 0 53.3 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 93.3 0 80 N.A. 26.6 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.7 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 0 0 15 8 8 0 0 0 8 50 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 0 0 0 58 0 0 0 15 58 8 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 58 0 0 0 0 0 0 15 0 % H
% Ile: 0 8 8 8 58 0 0 0 8 0 0 8 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 8 0 8 0 0 0 0 0 15 58 % L
% Met: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 15 0 0 8 0 0 0 8 0 15 50 0 0 0 % N
% Pro: 43 8 0 0 8 50 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 8 29 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 22 0 % R
% Ser: 0 50 8 8 0 0 8 58 8 0 0 8 0 0 0 % S
% Thr: 0 0 8 0 0 8 8 0 0 0 8 8 0 0 15 % T
% Val: 0 0 58 0 8 0 0 0 0 15 65 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 8 50 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _