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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
34.85
Human Site:
S442
Identified Species:
58.97
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
S442
R
Q
R
R
Y
L
E
S
A
R
C
Y
A
L
T
Chimpanzee
Pan troglodytes
XP_523187
973
110161
S442
R
Q
R
R
Y
L
E
S
A
R
C
Y
A
L
T
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
S442
R
Q
R
R
Y
L
E
S
A
R
C
Y
A
L
T
Dog
Lupus familis
XP_544627
1095
122945
S564
R
Q
R
R
Y
L
E
S
A
R
C
Y
A
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
S442
R
Q
H
R
Y
L
E
S
A
R
C
Y
A
L
T
Rat
Rattus norvegicus
NP_001099969
973
110167
S442
R
Q
H
R
Y
L
E
S
A
R
C
Y
A
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
D160
D
V
W
R
T
Y
L
D
M
N
R
F
D
L
A
Chicken
Gallus gallus
XP_421131
974
112556
S442
Q
N
K
R
Y
L
D
S
A
K
C
Y
A
L
T
Frog
Xenopus laevis
NP_001085645
968
111576
S437
Q
S
K
K
Y
I
E
S
A
K
C
Y
A
L
T
Zebra Danio
Brachydanio rerio
P59015
974
113248
S442
Q
N
K
R
Y
L
E
S
A
K
C
Y
A
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
A471
A
D
G
S
Y
Q
V
A
A
D
Y
Y
A
E
T
Honey Bee
Apis mellifera
XP_396968
718
83450
H266
S
N
N
T
S
Y
L
H
D
S
Q
Y
L
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
A417
D
K
E
Y
L
R
A
A
S
F
Y
A
K
I
N
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
L408
G
E
I
A
L
N
F
L
Q
I
K
D
Y
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
66.6
60
73.3
N.A.
33.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
93.3
93.3
93.3
N.A.
40
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
15
72
0
0
8
72
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% C
% Asp:
15
8
0
0
0
0
8
8
8
8
0
8
8
0
8
% D
% Glu:
0
8
8
0
0
0
58
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
8
0
0
0
8
0
% I
% Lys:
0
8
22
8
0
0
0
0
0
22
8
0
8
0
0
% K
% Leu:
0
0
0
0
15
58
15
8
0
0
0
0
8
72
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
22
8
0
0
8
0
0
0
8
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
22
43
0
0
0
8
0
0
8
0
8
0
0
0
0
% Q
% Arg:
43
0
29
65
0
8
0
0
0
43
8
0
0
0
0
% R
% Ser:
8
8
0
8
8
0
0
65
8
8
0
0
0
0
0
% S
% Thr:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
72
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
72
15
0
0
0
0
15
79
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _