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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
24.55
Human Site:
T58
Identified Species:
41.54
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
T58
F
T
P
S
E
R
I
T
S
L
V
V
S
S
N
Chimpanzee
Pan troglodytes
XP_523187
973
110161
T58
F
T
P
S
E
R
I
T
S
L
V
V
S
S
N
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
T58
F
T
P
S
E
R
I
T
S
L
V
V
S
S
N
Dog
Lupus familis
XP_544627
1095
122945
T180
F
T
P
S
E
R
I
T
S
L
V
V
S
C
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
T58
F
T
P
S
E
R
I
T
S
L
V
V
S
C
N
Rat
Rattus norvegicus
NP_001099969
973
110167
T58
F
T
P
S
E
R
I
T
S
L
V
V
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
Chicken
Gallus gallus
XP_421131
974
112556
N58
F
T
P
P
E
K
I
N
S
L
V
V
S
S
N
Frog
Xenopus laevis
NP_001085645
968
111576
S58
S
P
P
E
N
I
N
S
L
V
V
C
S
N
Q
Zebra Danio
Brachydanio rerio
P59015
974
113248
N58
F
S
P
P
E
K
I
N
Q
F
S
V
C
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
T59
L
R
V
P
S
N
C
T
G
D
L
M
H
L
A
Honey Bee
Apis mellifera
XP_396968
718
83450
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
L58
G
S
S
N
D
I
D
L
A
V
G
R
T
G
E
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
K58
H
F
D
C
P
L
S
K
E
L
E
T
I
M
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
0
80
20
40
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
86.6
40
60
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
8
8
22
0
% C
% Asp:
0
0
8
0
8
0
8
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
8
58
0
0
0
8
0
8
0
0
0
8
% E
% Phe:
58
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
8
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
15
58
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
15
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
8
0
8
8
58
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
8
8
8
8
15
0
0
0
0
0
15
58
% N
% Pro:
0
8
65
22
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
8
0
0
0
43
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
15
8
43
8
0
8
8
50
0
8
0
58
29
8
% S
% Thr:
0
50
0
0
0
0
0
50
0
0
0
8
8
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
15
58
58
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _