Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS18 All Species: 36.36
Human Site: Y695 Identified Species: 61.54
UniProt: Q9P253 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P253 NP_065908.1 973 110186 Y695 A S P H R V H Y D L K Y A L R
Chimpanzee Pan troglodytes XP_523187 973 110161 Y695 A S P H R V H Y D L K Y A L R
Rhesus Macaque Macaca mulatta XP_001099146 973 110096 Y695 A S P H R V H Y D L K Y A L R
Dog Lupus familis XP_544627 1095 122945 Y817 A S P H R V H Y D L K Y A L R
Cat Felis silvestris
Mouse Mus musculus Q8R307 973 110200 Y695 A S P H R V H Y D L K Y A L R
Rat Rattus norvegicus NP_001099969 973 110167 Y695 A S P H R V H Y D L K Y A L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506026 612 69591 G394 V N S S G P A G E A Q S V G Q
Chicken Gallus gallus XP_421131 974 112556 Y695 T N P N R I H Y D L K Y A L R
Frog Xenopus laevis NP_001085645 968 111576 Y689 T N T N R I H Y D L K Y A L R
Zebra Danio Brachydanio rerio P59015 974 113248 Y695 T H V S D I H Y D L K Y A L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24314 1002 115316 Y728 R D E S L V H Y D I Y Y A H K
Honey Bee Apis mellifera XP_396968 718 83450 H500 I A A M P S D H E L R K K L W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172709 994 113061 G673 F G K G R E N G P E F F Y D P
Baker's Yeast Sacchar. cerevisiae P27801 918 107380 L663 S N E N K Y D L N F Q L R L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.6 86.6 N.A. 95.7 95.1 N.A. 52.8 74 68.3 65.9 N.A. 34.7 34.6 N.A. N.A.
Protein Similarity: 100 99.9 99.9 87.4 N.A. 97.5 97.1 N.A. 56.4 86.4 83.2 82.4 N.A. 53.6 51.4 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 73.3 66.6 60 N.A. 40 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 93.3 86.6 66.6 N.A. 53.3 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.7 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. 52.3 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 8 8 0 0 0 8 0 0 8 0 0 72 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 15 0 72 0 0 0 0 8 0 % D
% Glu: 0 0 15 0 0 8 0 0 15 8 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % F
% Gly: 0 8 0 8 8 0 0 15 0 0 0 0 0 8 0 % G
% His: 0 8 0 43 0 0 72 8 0 0 0 0 0 8 0 % H
% Ile: 8 0 0 0 0 22 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 8 0 8 0 0 0 0 0 65 8 8 0 8 % K
% Leu: 0 0 0 0 8 0 0 8 0 72 0 8 0 79 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 29 0 22 0 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 50 0 8 8 0 0 8 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 8 % Q
% Arg: 8 0 0 0 65 0 0 0 0 0 8 0 8 0 65 % R
% Ser: 8 43 8 22 0 8 0 0 0 0 0 8 0 0 8 % S
% Thr: 22 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 8 0 0 50 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 8 0 72 0 0 8 72 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _