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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCC2
All Species:
41.52
Human Site:
S353
Identified Species:
76.11
UniProt:
Q9P258
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P258
NP_001129676.1
522
56085
S353
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Chimpanzee
Pan troglodytes
XP_513117
488
53080
S319
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544537
522
56002
S353
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BK67
520
55965
S351
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Rat
Rattus norvegicus
XP_216557
545
58657
S376
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506220
495
53703
S326
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Chicken
Gallus gallus
XP_417522
464
50419
Q309
G
R
L
G
H
A
E
Q
K
D
E
M
V
P
R
Frog
Xenopus laevis
Q52KW8
513
55477
S344
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Zebra Danio
Brachydanio rerio
Q6NYE2
495
54133
S326
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608985
487
53441
S320
D
S
K
K
R
V
Y
S
W
G
F
G
G
F
G
Honey Bee
Apis mellifera
XP_392946
486
52627
S321
D
S
K
N
R
A
F
S
W
G
F
G
G
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791849
452
49195
K297
Y
G
R
L
G
H
Q
K
P
D
D
E
P
V
P
Poplar Tree
Populus trichocarpa
XP_002306909
539
57109
S339
W
N
L
R
C
M
D
S
G
N
M
H
H
F
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85
N.A.
98.6
N.A.
95.9
79.4
N.A.
70.8
79.6
78.9
78.3
N.A.
43.6
44.4
N.A.
43.8
Protein Similarity:
100
86.4
N.A.
99.4
N.A.
97.6
83.3
N.A.
77
83.5
86.5
86.2
N.A.
59
59.9
N.A.
60.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
0
100
100
N.A.
80
73.3
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
0
100
100
N.A.
100
80
N.A.
6.6
Percent
Protein Identity:
22.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
77
0
0
0
0
0
8
0
0
16
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
70
0
0
0
77
0
0
16
0
% F
% Gly:
8
8
0
8
8
0
0
0
8
77
0
77
77
0
77
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
16
70
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
8
% P
% Gln:
0
0
62
0
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
8
77
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
77
0
0
0
0
0
85
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
70
0
0
0
0
0
0
8
8
8
% V
% Trp:
8
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
0
0
0
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _