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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCC2 All Species: 10.91
Human Site: S44 Identified Species: 20
UniProt: Q9P258 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P258 NP_001129676.1 522 56085 S44 E R P E R C S S S S G G G S S
Chimpanzee Pan troglodytes XP_513117 488 53080 L29 L K G Y V T K L L E A A R L A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544537 522 56002 S45 E R P E R C S S S S G G G S S
Cat Felis silvestris
Mouse Mus musculus Q8BK67 520 55965 S42 E R P E R C S S S S G G G S S
Rat Rattus norvegicus XP_216557 545 58657 R72 S K A T I F Q R V S S G P A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506220 495 53703 Y29 I I I T A M K Y R G A K A R R
Chicken Gallus gallus XP_417522 464 50419 V22 P H A K N L L V A D I A A D L
Frog Xenopus laevis Q52KW8 513 55477 D40 S R H E F S S D E D D L D G S
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 S30 K K K E R E F S S D D E F D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608985 487 53441 F30 E S D Y E D E F S D E S D D D
Honey Bee Apis mellifera XP_392946 486 52627 E30 D E E D I S S E H D S D V D D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791849 452 49195 G10 R G K K R S P G E E G D S K R
Poplar Tree Populus trichocarpa XP_002306909 539 57109 W31 L F C G A T C W N V V G R K K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 N.A. 98.6 N.A. 95.9 79.4 N.A. 70.8 79.6 78.9 78.3 N.A. 43.6 44.4 N.A. 43.8
Protein Similarity: 100 86.4 N.A. 99.4 N.A. 97.6 83.3 N.A. 77 83.5 86.5 86.2 N.A. 59 59.9 N.A. 60.3
P-Site Identity: 100 0 N.A. 100 N.A. 100 13.3 N.A. 0 0 26.6 26.6 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 33.3 N.A. 0 13.3 26.6 40 N.A. 13.3 20 N.A. 20
Percent
Protein Identity: 22.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 33.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 16 0 0 0 8 0 16 16 16 8 16 % A
% Cys: 0 0 8 0 0 24 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 8 0 8 0 8 0 39 16 16 16 31 24 % D
% Glu: 31 8 8 39 8 8 8 8 16 16 8 8 0 0 0 % E
% Phe: 0 8 0 0 8 8 8 8 0 0 0 0 8 0 0 % F
% Gly: 0 8 8 8 0 0 0 8 0 8 31 39 24 8 0 % G
% His: 0 8 8 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 16 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 24 16 16 0 0 16 0 0 0 0 8 0 16 8 % K
% Leu: 16 0 0 0 0 8 8 8 8 0 0 8 0 8 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 8 0 24 0 0 0 8 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 8 31 0 0 39 0 0 8 8 0 0 0 16 8 16 % R
% Ser: 16 8 0 0 0 24 39 31 39 31 16 8 8 24 31 % S
% Thr: 0 0 0 16 0 16 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 0 8 8 8 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 16 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _