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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCC2 All Species: 32.73
Human Site: S486 Identified Species: 60
UniProt: Q9P258 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P258 NP_001129676.1 522 56085 S486 K T L D G I F S E Q V A M G Y
Chimpanzee Pan troglodytes XP_513117 488 53080 S452 K T L D G I F S E Q V A M G Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544537 522 56002 T486 K T L D G I F T E Q V A M G Y
Cat Felis silvestris
Mouse Mus musculus Q8BK67 520 55965 S484 K T L D G I F S E Q V A M G Y
Rat Rattus norvegicus XP_216557 545 58657 S509 K T L D G I F S E Q V A M G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506220 495 53703 T459 K T L D G I Y T E Q V A M G Y
Chicken Gallus gallus XP_417522 464 50419 E429 T L D G I Y T E Q V A M G Y A
Frog Xenopus laevis Q52KW8 513 55477 S477 K T L D G I Y S D Q V I M G N
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 S459 K T L D G V Y S E Q V V M G Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608985 487 53441 I452 P K L D N I K I P Q V T M G Y
Honey Bee Apis mellifera XP_392946 486 52627 L451 E V K A L E G L Y I T A V T C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791849 452 49195 V417 R P L D N I Y V H H L T C G A
Poplar Tree Populus trichocarpa XP_002306909 539 57109 S460 K S K D A S E S E E E N S N D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 N.A. 98.6 N.A. 95.9 79.4 N.A. 70.8 79.6 78.9 78.3 N.A. 43.6 44.4 N.A. 43.8
Protein Similarity: 100 86.4 N.A. 99.4 N.A. 97.6 83.3 N.A. 77 83.5 86.5 86.2 N.A. 59 59.9 N.A. 60.3
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 86.6 0 73.3 80 N.A. 53.3 6.6 N.A. 26.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 6.6 86.6 93.3 N.A. 53.3 20 N.A. 46.6
Percent
Protein Identity: 22.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 33.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 40 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 0 0 0 8 54 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % C
% Asp: 0 0 8 85 0 0 0 0 8 0 0 0 0 0 8 % D
% Glu: 8 0 0 0 0 8 8 8 62 8 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 39 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 62 0 8 0 0 0 0 0 8 77 0 % G
% His: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 70 0 8 0 8 0 8 0 0 0 % I
% Lys: 70 8 16 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 77 0 8 0 0 8 0 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 70 0 0 % M
% Asn: 0 0 0 0 16 0 0 0 0 0 0 8 0 8 8 % N
% Pro: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 70 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 8 0 54 0 0 0 0 8 0 0 % S
% Thr: 8 62 0 0 0 0 8 16 0 0 8 16 0 8 0 % T
% Val: 0 8 0 0 0 8 0 8 0 8 70 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 31 0 8 0 0 0 0 8 62 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _