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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RCC2 All Species: 16.67
Human Site: T91 Identified Species: 30.56
UniProt: Q9P258 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P258 NP_001129676.1 522 56085 T91 V I T E P E H T K E R V K L E
Chimpanzee Pan troglodytes XP_513117 488 53080 C68 L K L E G S K C K G Q L L I F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544537 522 56002 T91 V I T E P E H T K E R V K L E
Cat Felis silvestris
Mouse Mus musculus Q8BK67 520 55965 T89 I I T E P E H T K E R V K L E
Rat Rattus norvegicus XP_216557 545 58657 G114 S G G R P G R G D L R P K L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506220 495 53703 E68 G T S V R G P E K G G K D H D
Chicken Gallus gallus XP_417522 464 50419 R61 T N W D L I G R K E V P K Q Q
Frog Xenopus laevis Q52KW8 513 55477 S82 I V T E P E H S K E K I K L E
Zebra Danio Brachydanio rerio Q6NYE2 495 54133 K69 D D V K E K I K L E V P K V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608985 487 53441 T71 L P E D L L A T L E K T P G Q
Honey Bee Apis mellifera XP_392946 486 52627 G69 E L P P P E G G W G K P G T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791849 452 49195 S49 E T I K L K D S P F V G T L L
Poplar Tree Populus trichocarpa XP_002306909 539 57109 C71 S G S A S C H C V A L D V E G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 N.A. 98.6 N.A. 95.9 79.4 N.A. 70.8 79.6 78.9 78.3 N.A. 43.6 44.4 N.A. 43.8
Protein Similarity: 100 86.4 N.A. 99.4 N.A. 97.6 83.3 N.A. 77 83.5 86.5 86.2 N.A. 59 59.9 N.A. 60.3
P-Site Identity: 100 13.3 N.A. 100 N.A. 93.3 33.3 N.A. 6.6 20 66.6 13.3 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 40 N.A. 100 N.A. 100 33.3 N.A. 20 33.3 100 40 N.A. 40 26.6 N.A. 26.6
Percent
Protein Identity: 22.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 33.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 16 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 16 0 0 8 0 8 0 0 8 8 0 8 % D
% Glu: 16 0 8 39 8 39 0 8 0 54 0 0 0 8 39 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % F
% Gly: 8 16 8 0 8 16 16 16 0 24 8 8 8 8 8 % G
% His: 0 0 0 0 0 0 39 0 0 0 0 0 0 8 0 % H
% Ile: 16 24 8 0 0 8 8 0 0 0 0 8 0 8 0 % I
% Lys: 0 8 0 16 0 16 8 8 54 0 24 8 54 0 8 % K
% Leu: 16 8 8 0 24 8 0 0 16 8 8 8 8 47 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 8 8 47 0 8 0 8 0 0 31 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 16 % Q
% Arg: 0 0 0 8 8 0 8 8 0 0 31 0 0 0 0 % R
% Ser: 16 0 16 0 8 8 0 16 0 0 0 0 0 0 0 % S
% Thr: 8 16 31 0 0 0 0 31 0 0 0 8 8 8 0 % T
% Val: 16 8 8 8 0 0 0 0 8 0 24 24 8 8 0 % V
% Trp: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _