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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1468 All Species: 22.42
Human Site: T349 Identified Species: 41.11
UniProt: Q9P260 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P260 NP_065905.2 1216 134630 T349 N L P P T L E T P Q P A E N S
Chimpanzee Pan troglodytes XP_001144840 1216 134598 T349 N L P P T L E T P Q P A E N S
Rhesus Macaque Macaca mulatta XP_001089393 1216 134711 T349 N L P P T L E T P Q P A E N S
Dog Lupus familis XP_857532 1213 134286 T350 N L P P S L E T P Q T V E N S
Cat Felis silvestris
Mouse Mus musculus Q148V7 1216 134568 T349 N V P P T L D T P L P I E N T
Rat Rattus norvegicus NP_001128018 1218 134632 T349 N I P P T L D T P L P I E N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520447 566 63684
Chicken Gallus gallus XP_418993 1101 123185 G316 S E N D S K H G N T E E K S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6P6Y1 1189 132113 I323 P V Q Q T D V I Q Q Q Q Q Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624982 1101 123579 E316 D T S T V T Q E V E E D D S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188840 523 57914
Poplar Tree Populus trichocarpa XP_002305839 1140 127435 S319 S D V D A V Q S Q S L E K Y K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197125 1180 132290 L318 N E G D P V K L Q S K E V E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.4 95.6 N.A. 93.3 92.6 N.A. 44.1 80 N.A. 74.5 N.A. N.A. 32.3 N.A. 23.5
Protein Similarity: 100 99.9 98.2 97.3 N.A. 95.9 95.5 N.A. 45.1 84.2 N.A. 83.3 N.A. N.A. 50.6 N.A. 31.9
P-Site Identity: 100 100 100 80 N.A. 66.6 73.3 N.A. 0 0 N.A. 13.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 0 26.6 N.A. 26.6 N.A. N.A. 33.3 N.A. 0
Percent
Protein Identity: 23.3 N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. 41.6 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 0 24 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 24 0 8 16 0 0 0 0 8 8 0 0 % D
% Glu: 0 16 0 0 0 0 31 8 0 8 16 24 47 8 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 0 16 0 0 0 % I
% Lys: 0 0 0 0 0 8 8 0 0 0 8 0 16 0 8 % K
% Leu: 0 31 0 0 0 47 0 8 0 16 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 54 0 8 0 0 0 0 0 8 0 0 0 0 47 0 % N
% Pro: 8 0 47 47 8 0 0 0 47 0 39 0 0 0 0 % P
% Gln: 0 0 8 8 0 0 16 0 24 39 8 8 8 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 0 8 0 16 0 0 8 0 16 0 0 0 16 39 % S
% Thr: 0 8 0 8 47 8 0 47 0 8 8 0 0 0 8 % T
% Val: 0 16 8 0 8 16 8 0 8 0 0 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _