KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP36
All Species:
10.3
Human Site:
S490
Identified Species:
20.61
UniProt:
Q9P275
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P275
NP_079366.3
1121
122652
S490
E
E
I
G
V
P
I
S
R
N
G
S
T
L
G
Chimpanzee
Pan troglodytes
XP_001146571
1275
138595
S490
E
E
I
G
V
P
I
S
R
N
G
S
T
L
G
Rhesus Macaque
Macaca mulatta
XP_001108648
1126
122953
S493
E
E
V
G
V
P
I
S
R
N
G
S
T
L
G
Dog
Lupus familis
XP_540463
1117
122160
R490
E
L
G
V
P
V
S
R
N
G
S
V
S
G
P
Cat
Felis silvestris
Mouse
Mus musculus
B1AQJ2
1098
119895
R490
E
V
G
V
P
V
S
R
N
G
S
L
P
G
L
Rat
Rattus norvegicus
NP_001100539
1005
109039
Y416
V
V
L
S
Q
Q
A
Y
V
L
F
Y
L
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520693
1068
115594
G476
I
G
K
R
Q
D
G
G
P
R
K
K
P
Q
V
Chicken
Gallus gallus
XP_424101
643
69042
A54
V
S
L
E
I
R
Q
A
A
N
I
V
R
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688241
1104
122640
S490
V
P
V
A
R
N
C
S
G
L
Q
S
P
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRP5
1085
118669
R460
N
F
D
D
S
Y
V
R
P
I
A
M
H
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795476
1126
125182
P504
T
S
N
A
P
I
T
P
K
P
K
I
I
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPS4
859
94885
A270
K
A
D
S
L
Q
R
A
L
S
R
F
T
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
92
74.6
N.A.
71.8
67.4
N.A.
62.1
37.8
N.A.
47.6
N.A.
24.5
N.A.
N.A.
27.8
Protein Similarity:
100
81.4
94.4
83.1
N.A.
80.4
75.3
N.A.
70.6
45.2
N.A.
61.7
N.A.
43.2
N.A.
N.A.
44.2
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
0
N.A.
0
6.6
N.A.
13.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
0
26.6
N.A.
20
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
0
9
17
9
0
9
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
9
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
42
25
0
9
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
9
9
0
0
0
% F
% Gly:
0
9
17
25
0
0
9
9
9
17
25
0
0
17
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
17
0
9
9
25
0
0
9
9
9
9
0
9
% I
% Lys:
9
0
9
0
0
0
0
0
9
0
17
9
0
9
0
% K
% Leu:
0
9
17
0
9
0
0
0
9
17
0
9
9
25
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
0
9
0
0
9
0
0
17
34
0
0
0
0
0
% N
% Pro:
0
9
0
0
25
25
0
9
17
9
0
0
25
0
9
% P
% Gln:
0
0
0
0
17
17
9
0
0
0
9
0
0
9
0
% Q
% Arg:
0
0
0
9
9
9
9
25
25
9
9
0
9
17
0
% R
% Ser:
0
17
0
17
9
0
17
34
0
9
17
34
9
9
0
% S
% Thr:
9
0
0
0
0
0
9
0
0
0
0
0
34
0
0
% T
% Val:
25
17
17
17
25
17
9
0
9
0
0
17
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
9
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _