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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP36 All Species: 10.3
Human Site: S494 Identified Species: 20.61
UniProt: Q9P275 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P275 NP_079366.3 1121 122652 S494 V P I S R N G S T L G L K S Q
Chimpanzee Pan troglodytes XP_001146571 1275 138595 S494 V P I S R N G S T L G L K S Q
Rhesus Macaque Macaca mulatta XP_001108648 1126 122953 S497 V P I S R N G S T L G L K S Q
Dog Lupus familis XP_540463 1117 122160 V494 P V S R N G S V S G P K S Q N
Cat Felis silvestris
Mouse Mus musculus B1AQJ2 1098 119895 L494 P V S R N G S L P G L K L Q N
Rat Rattus norvegicus NP_001100539 1005 109039 Y420 Q Q A Y V L F Y L R I P G S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520693 1068 115594 K480 Q D G G P R K K P Q V T E E T
Chicken Gallus gallus XP_424101 643 69042 V58 I R Q A A N I V R A L E L F V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688241 1104 122640 S494 R N C S G L Q S P K L S N G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP5 1085 118669 M464 S Y V R P I A M H S V C N T N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795476 1126 125182 I508 P I T P K P K I I R E P E K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FPS4 859 94885 F274 L Q R A L S R F T A V E L L D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 92 74.6 N.A. 71.8 67.4 N.A. 62.1 37.8 N.A. 47.6 N.A. 24.5 N.A. N.A. 27.8
Protein Similarity: 100 81.4 94.4 83.1 N.A. 80.4 75.3 N.A. 70.6 45.2 N.A. 61.7 N.A. 43.2 N.A. N.A. 44.2
P-Site Identity: 100 100 100 0 N.A. 0 6.6 N.A. 0 6.6 N.A. 13.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 6.6 N.A. 0 13.3 N.A. 6.6 20 N.A. 13.3 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 17 9 0 9 0 0 17 0 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 17 17 9 0 % E
% Phe: 0 0 0 0 0 0 9 9 0 0 0 0 0 9 0 % F
% Gly: 0 0 9 9 9 17 25 0 0 17 25 0 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 9 9 25 0 0 9 9 9 9 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 17 9 0 9 0 17 25 9 17 % K
% Leu: 9 0 0 0 9 17 0 9 9 25 25 25 25 9 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 17 34 0 0 0 0 0 0 17 0 25 % N
% Pro: 25 25 0 9 17 9 0 0 25 0 9 17 0 0 0 % P
% Gln: 17 17 9 0 0 0 9 0 0 9 0 0 0 17 25 % Q
% Arg: 9 9 9 25 25 9 9 0 9 17 0 0 0 0 0 % R
% Ser: 9 0 17 34 0 9 17 34 9 9 0 9 9 34 0 % S
% Thr: 0 0 9 0 0 0 0 0 34 0 0 9 0 9 17 % T
% Val: 25 17 9 0 9 0 0 17 0 0 25 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 9 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _