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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP36
All Species:
14.55
Human Site:
S646
Identified Species:
29.09
UniProt:
Q9P275
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P275
NP_079366.3
1121
122652
S646
D
S
Q
E
T
N
C
S
T
A
G
H
S
K
T
Chimpanzee
Pan troglodytes
XP_001146571
1275
138595
S646
G
S
Q
E
T
N
C
S
T
A
G
P
S
K
T
Rhesus Macaque
Macaca mulatta
XP_001108648
1126
122953
S649
D
S
Q
E
T
N
C
S
T
A
G
H
S
K
T
Dog
Lupus familis
XP_540463
1117
122160
S647
D
S
Q
G
T
H
S
S
A
A
G
H
S
R
A
Cat
Felis silvestris
Mouse
Mus musculus
B1AQJ2
1098
119895
P642
D
S
Q
G
T
N
C
P
T
A
G
H
P
K
A
Rat
Rattus norvegicus
NP_001100539
1005
109039
W568
R
S
Q
R
P
G
S
W
A
S
R
D
S
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520693
1068
115594
P628
D
A
G
A
R
G
P
P
T
P
R
G
G
A
A
Chicken
Gallus gallus
XP_424101
643
69042
S206
I
P
G
P
R
K
G
S
E
G
P
I
A
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688241
1104
122640
R642
S
A
K
K
A
S
V
R
Q
S
L
S
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRP5
1085
118669
S615
Q
Q
Y
L
P
I
S
S
D
D
E
D
I
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795476
1126
125182
T658
T
T
V
M
T
K
T
T
V
M
T
K
A
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPS4
859
94885
V422
V
P
K
N
S
V
P
V
V
K
K
E
S
F
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
92
74.6
N.A.
71.8
67.4
N.A.
62.1
37.8
N.A.
47.6
N.A.
24.5
N.A.
N.A.
27.8
Protein Similarity:
100
81.4
94.4
83.1
N.A.
80.4
75.3
N.A.
70.6
45.2
N.A.
61.7
N.A.
43.2
N.A.
N.A.
44.2
P-Site Identity:
100
86.6
100
60
N.A.
73.3
20
N.A.
13.3
13.3
N.A.
13.3
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
86.6
100
73.3
N.A.
73.3
26.6
N.A.
20
20
N.A.
46.6
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
9
0
0
0
17
42
0
0
17
9
42
% A
% Cys:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
0
0
0
0
0
0
9
9
0
17
0
0
9
% D
% Glu:
0
0
0
25
0
0
0
0
9
0
9
9
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% F
% Gly:
9
0
17
17
0
17
9
0
0
9
42
9
9
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
34
0
0
0
% H
% Ile:
9
0
0
0
0
9
0
0
0
0
0
9
9
9
0
% I
% Lys:
0
0
17
9
0
17
0
0
0
9
9
9
0
42
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
34
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
0
9
17
0
17
17
0
9
9
9
9
0
0
% P
% Gln:
9
9
50
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
17
0
0
9
0
0
17
0
0
9
0
% R
% Ser:
9
50
0
0
9
9
25
50
0
17
0
9
59
9
0
% S
% Thr:
9
9
0
0
50
0
9
9
42
0
9
0
0
9
34
% T
% Val:
9
0
9
0
0
9
9
9
17
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _