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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 10.3
Human Site: S183 Identified Species: 16.19
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S183 K H G E A Y Y S E V K P L K S
Chimpanzee Pan troglodytes XP_525261 777 87548 S241 K H G E A Y Y S E V K P L K S
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S241 K H G E A Y Y S E M K P L K S
Dog Lupus familis XP_542895 719 81009 P183 K H G E A H Y P E M K P W K S
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 P183 K H G D A Y Y P E M K S L K T
Rat Rattus norvegicus P35465 544 60559 D30 M I G A G S K D P G T L N H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 M185 D D T Y Y S D M R L F K S D I
Chicken Gallus gallus XP_415031 787 88575 P251 I Y Y S E M T P L K S D L S R
Frog Xenopus laevis NP_001082100 650 73749 S136 R E D G Q R G S E R N R S E H
Zebra Danio Brachydanio rerio NP_998127 711 78596 E186 P D Y H A Y L E S R T Q L C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 P125 G P G M M M P P E T G G I V L
Honey Bee Apis mellifera XP_001122147 624 70155 R110 V A R S N S L R S S S P P K L
Nematode Worm Caenorhab. elegans Q17850 572 63863 K58 F M K K N K D K K E A S E K P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 K354 H H V G V D S K T G E Y T G L
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 D408 Q Q L E K F H D A R A T D F R
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 66.6 6.6 N.A. 0 6.6 13.3 20 N.A. 13.3 13.3 6.6 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 6.6 N.A. 6.6 13.3 26.6 20 N.A. 20 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 40 0 0 0 7 0 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 7 14 7 7 0 7 14 14 0 0 0 7 7 7 0 % D
% Glu: 0 7 0 34 7 0 0 7 47 7 7 0 7 7 0 % E
% Phe: 7 0 0 0 0 7 0 0 0 0 7 0 0 7 0 % F
% Gly: 7 0 47 14 7 0 7 0 0 14 7 7 0 7 14 % G
% His: 7 40 0 7 0 7 7 0 0 0 0 0 0 7 7 % H
% Ile: 7 7 0 0 0 0 0 0 0 0 0 0 7 0 7 % I
% Lys: 34 0 7 7 7 7 7 14 7 7 34 7 0 47 0 % K
% Leu: 0 0 7 0 0 0 14 0 7 7 0 7 40 0 20 % L
% Met: 7 7 0 7 7 14 0 7 0 20 0 0 0 0 0 % M
% Asn: 0 0 0 0 14 0 0 0 0 0 7 0 7 0 0 % N
% Pro: 7 7 0 0 0 0 7 27 7 0 0 34 7 0 7 % P
% Gln: 7 7 0 0 7 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 7 0 7 0 0 7 0 7 7 20 0 7 0 0 14 % R
% Ser: 0 0 0 14 0 20 7 27 14 7 14 14 14 7 27 % S
% Thr: 0 0 7 0 0 0 7 0 7 7 14 7 7 0 7 % T
% Val: 7 0 7 0 7 0 0 0 0 14 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 7 14 7 7 34 34 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _