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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 14.85
Human Site: S190 Identified Species: 23.33
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S190 S E V K P L K S D F A R F S A
Chimpanzee Pan troglodytes XP_525261 777 87548 S248 S E V K P L K S D F A R F S A
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S248 S E M K P L K S D F A R F S A
Dog Lupus familis XP_542895 719 81009 S190 P E M K P W K S D L A R F P L
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 T190 P E M K S L K T D L A G F P V
Rat Rattus norvegicus P35465 544 60559 G37 D P G T L N H G S K P L P P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 I192 M R L F K S D I S R F P S D Y
Chicken Gallus gallus XP_415031 787 88575 R258 P L K S D L S R F L P D Y H A
Frog Xenopus laevis NP_001082100 650 73749 H143 S E R N R S E H H R R E R Q R
Zebra Danio Brachydanio rerio NP_998127 711 78596 G193 E S R T Q L C G E G P V G R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 L132 P E T G G I V L P K T S H V A
Honey Bee Apis mellifera XP_001122147 624 70155 L117 R S S S P P K L R R D Y R H N
Nematode Worm Caenorhab. elegans Q17850 572 63863 P65 K K E A S E K P V I S R P S N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 L361 K T G E Y T G L P E E W E K L
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 R415 D A R A T D F R S P P V T G T
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 93.3 60 N.A. 46.6 0 N.A. 0 13.3 13.3 6.6 N.A. 13.3 13.3 20 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 60 0 N.A. 6.6 20 20 13.3 N.A. 20 13.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 0 0 0 0 0 0 34 0 0 0 34 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 0 7 7 7 0 34 0 7 7 0 7 0 % D
% Glu: 7 47 7 7 0 7 7 0 7 7 7 7 7 0 0 % E
% Phe: 0 0 0 7 0 0 7 0 7 20 7 0 34 0 0 % F
% Gly: 0 0 14 7 7 0 7 14 0 7 0 7 7 7 0 % G
% His: 0 0 0 0 0 0 7 7 7 0 0 0 7 14 0 % H
% Ile: 0 0 0 0 0 7 0 7 0 7 0 0 0 0 0 % I
% Lys: 14 7 7 34 7 0 47 0 0 14 0 0 0 7 0 % K
% Leu: 0 7 7 0 7 40 0 20 0 20 0 7 0 0 14 % L
% Met: 7 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 20 % N
% Pro: 27 7 0 0 34 7 0 7 14 7 27 7 14 20 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 7 7 20 0 7 0 0 14 7 20 7 34 14 7 14 % R
% Ser: 27 14 7 14 14 14 7 27 20 0 7 7 7 27 0 % S
% Thr: 0 7 7 14 7 7 0 7 0 0 7 0 7 0 7 % T
% Val: 0 0 14 0 0 0 7 0 7 0 0 14 0 7 7 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 7 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _