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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 10.91
Human Site: S196 Identified Species: 17.14
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S196 K S D F A R F S A D Y H S H L
Chimpanzee Pan troglodytes XP_525261 777 87548 S254 K S D F A R F S A D Y H S H L
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S254 K S D F A R F S A D Y H S H L
Dog Lupus familis XP_542895 719 81009 P196 K S D L A R F P L D Y H T H L
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 P196 K T D L A G F P V D Y H T H L
Rat Rattus norvegicus P35465 544 60559 P43 H G S K P L P P N P E E K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 D198 D I S R F P S D Y H A H M E A
Chicken Gallus gallus XP_415031 787 88575 H264 S R F L P D Y H A Q V E A K P
Frog Xenopus laevis NP_001082100 650 73749 Q149 E H H R R E R Q R E E H R A V
Zebra Danio Brachydanio rerio NP_998127 711 78596 R199 C G E G P V G R R D Y R A S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 V138 V L P K T S H V A R S N S L R
Honey Bee Apis mellifera XP_001122147 624 70155 H123 K L R R D Y R H N N N L P P S
Nematode Worm Caenorhab. elegans Q17850 572 63863 S71 K P V I S R P S N F E H T I H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 K367 G L P E E W E K L L T S S G I
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 G421 F R S P P V T G T A P L V L Q
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 73.3 N.A. 60 0 N.A. 6.6 6.6 6.6 20 N.A. 13.3 6.6 26.6 N.A.
P-Site Similarity: 100 100 100 80 N.A. 73.3 0 N.A. 6.6 20 26.6 33.3 N.A. 20 13.3 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 34 0 0 0 34 7 7 0 14 7 7 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 34 0 7 7 0 7 0 40 0 0 0 0 0 % D
% Glu: 7 0 7 7 7 7 7 0 0 7 20 14 0 7 0 % E
% Phe: 7 0 7 20 7 0 34 0 0 7 0 0 0 0 0 % F
% Gly: 7 14 0 7 0 7 7 7 0 0 0 0 0 7 0 % G
% His: 7 7 7 0 0 0 7 14 0 7 0 54 0 34 7 % H
% Ile: 0 7 0 7 0 0 0 0 0 0 0 0 0 7 7 % I
% Lys: 47 0 0 14 0 0 0 7 0 0 0 0 7 14 7 % K
% Leu: 0 20 0 20 0 7 0 0 14 7 0 14 0 14 40 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 20 7 7 7 0 0 0 % N
% Pro: 0 7 14 7 27 7 14 20 0 7 7 0 7 7 7 % P
% Gln: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 7 % Q
% Arg: 0 14 7 20 7 34 14 7 14 7 0 7 7 0 7 % R
% Ser: 7 27 20 0 7 7 7 27 0 0 7 7 34 7 7 % S
% Thr: 0 7 0 0 7 0 7 0 7 0 7 0 20 0 0 % T
% Val: 7 0 7 0 0 14 0 7 7 0 7 0 7 0 7 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 7 0 7 0 40 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _