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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 19.39
Human Site: S224 Identified Species: 30.48
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S224 W E Y Q R A S S S S P L D Y S
Chimpanzee Pan troglodytes XP_525261 777 87548 S282 W E Y Q R A S S S S P L D Y S
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S282 W E Y Q R A S S S S P L D Y S
Dog Lupus familis XP_542895 719 81009 S224 W E Y Q R A S S S S P L D Y P
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S224 W D Y Q R A S S S S P L D Y S
Rat Rattus norvegicus P35465 544 60559 E71 T N K K K E K E R P E I S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 S226 Y Q R V S S A S P L D Y R D P
Chicken Gallus gallus XP_415031 787 88575 L292 R I P S G S S L D Y R D P F P
Frog Xenopus laevis NP_001082100 650 73749 P177 R P P P P D Y P K D I P E K R
Zebra Danio Brachydanio rerio NP_998127 711 78596 R227 T P S R L S L R S D H T S C P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 E166 P P S V P E E E G P P A A G T
Honey Bee Apis mellifera XP_001122147 624 70155 F151 I Q S Y T T N F G K Q H N Y L
Nematode Worm Caenorhab. elegans Q17850 572 63863 L99 P E A W A R L L T D S Q I S K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 D395 D I V K F Y Q D V T E T N G E
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 R449 I S P P A S P R F P Q V G H E
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 0 N.A. 6.6 6.6 0 6.6 N.A. 6.6 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 20 N.A. 33.3 20 6.6 20 N.A. 13.3 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 14 34 7 0 0 0 0 7 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 7 7 0 0 0 7 0 7 7 20 7 7 34 7 0 % D
% Glu: 0 34 0 0 0 14 7 14 0 0 14 0 7 0 14 % E
% Phe: 0 0 0 0 7 0 0 7 7 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 7 0 0 0 14 0 0 0 7 14 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 7 0 7 0 % H
% Ile: 14 14 0 0 0 0 0 0 0 0 7 7 7 0 0 % I
% Lys: 0 0 7 14 7 0 7 0 7 7 0 0 0 7 7 % K
% Leu: 0 0 0 0 7 0 14 14 0 7 0 34 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 7 0 0 0 0 0 14 0 0 % N
% Pro: 14 20 20 14 14 0 7 7 7 20 40 7 7 0 34 % P
% Gln: 0 14 0 34 0 0 7 0 0 0 14 7 0 0 0 % Q
% Arg: 14 0 7 7 34 7 0 14 7 0 7 0 7 0 7 % R
% Ser: 0 7 20 7 7 27 40 40 40 34 7 0 14 7 27 % S
% Thr: 14 0 0 0 7 7 0 0 7 7 0 14 0 0 7 % T
% Val: 0 0 7 14 0 0 0 0 7 0 0 7 0 0 0 % V
% Trp: 34 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 34 7 0 7 7 0 0 7 0 7 0 40 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _