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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 27.88
Human Site: S270 Identified Species: 43.81
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S270 D Y D R R P K S S Y L N Q T S
Chimpanzee Pan troglodytes XP_525261 777 87548 S328 D Y D R R P K S S Y L N Q T S
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S328 D Y D R R P K S S Y L N Q T S
Dog Lupus familis XP_542895 719 81009 S270 D Y D R R P K S S Y L N Q T S
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S270 D Y D R R P K S S Y L H Q T S
Rat Rattus norvegicus P35465 544 60559 Q117 S N I T K S E Q K K N P Q A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 S272 D Y D K R P K S S Y V N K T S
Chicken Gallus gallus XP_415031 787 88575 S338 D Y D K R P K S S Y V D P A S
Frog Xenopus laevis NP_001082100 650 73749 P223 D K G E E K R P K S A Y T S G
Zebra Danio Brachydanio rerio NP_998127 711 78596 E273 R S G S G L Q E P S S S S G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 R212 A T G P L A V R T D Q T N L Q
Honey Bee Apis mellifera XP_001122147 624 70155 T197 M Q S S P N L T H V G S N A P
Nematode Worm Caenorhab. elegans Q17850 572 63863 P145 M M F I D D A P S R T P S Y G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 N441 P S T S D S H N Y G S R T G T
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 S495 A P K P P A I S T R P L V P P
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 6.6 N.A. 80 66.6 6.6 6.6 N.A. 0 0 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 100 86.6 20 20 N.A. 6.6 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 14 7 0 0 0 7 0 0 20 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 0 47 0 14 7 0 0 0 7 0 7 0 0 0 % D
% Glu: 0 0 0 7 7 0 7 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 20 0 7 0 0 0 0 7 7 0 0 14 14 % G
% His: 0 0 0 0 0 0 7 0 7 0 0 7 0 0 0 % H
% Ile: 0 0 7 7 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 7 14 7 7 47 0 14 7 0 0 7 0 0 % K
% Leu: 0 0 0 0 7 7 7 0 0 0 34 7 0 7 0 % L
% Met: 14 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 7 0 7 0 0 7 34 14 0 0 % N
% Pro: 7 7 0 14 14 47 0 14 7 0 7 14 7 7 14 % P
% Gln: 0 7 0 0 0 0 7 7 0 0 7 0 40 0 7 % Q
% Arg: 7 0 0 34 47 0 7 7 0 14 0 7 0 0 0 % R
% Ser: 7 14 7 20 0 14 0 54 54 14 14 14 14 7 54 % S
% Thr: 0 7 7 7 0 0 0 7 14 0 7 7 14 40 7 % T
% Val: 0 0 0 0 0 0 7 0 0 7 14 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 47 0 0 0 0 0 0 7 47 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _