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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 27.27
Human Site: S277 Identified Species: 42.86
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S277 S S Y L N Q T S P Q P T M R Q
Chimpanzee Pan troglodytes XP_525261 777 87548 S335 S S Y L N Q T S P Q P T M R Q
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S335 S S Y L N Q T S P Q P A M R Q
Dog Lupus familis XP_542895 719 81009 S277 S S Y L N Q T S P Q P T M R Q
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S277 S S Y L H Q T S P Q P A M R Q
Rat Rattus norvegicus P35465 544 60559 V124 Q K K N P Q A V L D V L E F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 S279 S S Y V N K T S P Q P A M R Q
Chicken Gallus gallus XP_415031 787 88575 S345 S S Y V D P A S P Q P T M R Q
Frog Xenopus laevis NP_001082100 650 73749 G230 P K S A Y T S G E G S P Q S P
Zebra Danio Brachydanio rerio NP_998127 711 78596 S280 E P S S S S G S S G A P Y S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 Q219 R T D Q T N L Q Q Y R S N L A
Honey Bee Apis mellifera XP_001122147 624 70155 P204 T H V G S N A P N L S L N F Q
Nematode Worm Caenorhab. elegans Q17850 572 63863 G152 P S R T P S Y G L K P Q P Y S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 T448 N Y G S R T G T P M S N H V M
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 P502 S T R P L V P P A S L P A K D
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 86.6 6.6 N.A. 80 73.3 0 6.6 N.A. 0 6.6 13.3 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 6.6 N.A. 93.3 86.6 6.6 13.3 N.A. 13.3 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 20 0 7 0 7 20 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 7 0 0 0 0 7 0 0 0 0 7 % D
% Glu: 7 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % F
% Gly: 0 0 7 7 0 0 14 14 0 14 0 0 0 0 0 % G
% His: 0 7 0 0 7 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 14 7 0 0 7 0 0 0 7 0 0 0 7 0 % K
% Leu: 0 0 0 34 7 0 7 0 14 7 7 14 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 47 0 7 % M
% Asn: 7 0 0 7 34 14 0 0 7 0 0 7 14 0 0 % N
% Pro: 14 7 0 7 14 7 7 14 54 0 54 20 7 0 7 % P
% Gln: 7 0 0 7 0 40 0 7 7 47 0 7 7 0 54 % Q
% Arg: 7 0 14 0 7 0 0 0 0 0 7 0 0 47 0 % R
% Ser: 54 54 14 14 14 14 7 54 7 7 20 7 0 14 7 % S
% Thr: 7 14 0 7 7 14 40 7 0 0 0 27 0 0 0 % T
% Val: 0 0 7 14 0 7 0 7 0 0 7 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 47 0 7 0 7 0 0 7 0 0 7 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _