Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 30.91
Human Site: S290 Identified Species: 48.57
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S290 R Q R S R S G S G L Q E P M M
Chimpanzee Pan troglodytes XP_525261 777 87548 S348 R Q R S R S G S G L Q E P M M
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S348 R Q R S R S G S G L Q E P M M
Dog Lupus familis XP_542895 719 81009 S290 R Q R S R S G S G L Q E P M M
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S290 R Q R S K S G S G L Q E P M M
Rat Rattus norvegicus P35465 544 60559 S137 F Y N S K K T S N S Q K Y M S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 S292 R Q R S R S G S G L Q E P I I
Chicken Gallus gallus XP_415031 787 88575 S358 R Q R S R S G S G L Q E P A M
Frog Xenopus laevis NP_001082100 650 73749 L243 S P R D K R P L S G P N I R T
Zebra Danio Brachydanio rerio NP_998127 711 78596 A293 S I S A L S A A P P Q G S Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S232 L A P P S G G S M P Q Q Q Q T
Honey Bee Apis mellifera XP_001122147 624 70155 N217 F Q N L S P I N T P Q C S I Q
Nematode Worm Caenorhab. elegans Q17850 572 63863 Y165 Y S T S S L P Y H G N K I Q D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 T461 V M S P T L N T D S S S A N G
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 P515 K D S G I G M P P P G D E A P
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 26.6 N.A. 86.6 93.3 6.6 13.3 N.A. 20 13.3 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 40 N.A. 100 93.3 13.3 26.6 N.A. 26.6 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 0 7 7 0 0 0 0 7 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 7 0 7 0 0 0 0 7 0 0 7 0 0 7 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 47 7 0 0 % E
% Phe: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 14 54 0 47 14 7 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 7 0 7 0 0 0 0 0 14 14 7 % I
% Lys: 7 0 0 0 20 7 0 0 0 0 0 14 0 0 0 % K
% Leu: 7 0 0 7 7 14 0 7 0 47 0 0 0 0 0 % L
% Met: 0 7 0 0 0 0 7 0 7 0 0 0 0 40 40 % M
% Asn: 0 0 14 0 0 0 7 7 7 0 7 7 0 7 0 % N
% Pro: 0 7 7 14 0 7 14 7 14 27 7 0 47 0 7 % P
% Gln: 0 54 0 0 0 0 0 0 0 0 74 7 7 14 7 % Q
% Arg: 47 0 54 0 40 7 0 0 0 0 0 0 0 7 0 % R
% Ser: 14 7 20 60 20 54 0 60 7 14 7 7 14 0 14 % S
% Thr: 0 0 7 0 7 0 7 7 7 0 0 0 0 0 14 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 0 0 0 7 0 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _