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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 26.36
Human Site: S368 Identified Species: 41.43
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S368 Q S K S G Y S S S S H Q Y P S
Chimpanzee Pan troglodytes XP_525261 777 87548 S426 Q S K S G Y S S S S H Q Y P S
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S426 Q S K A G Y S S S S H Q Y P S
Dog Lupus familis XP_542895 719 81009 S368 Q S K A G Y S S S S H Q Y P S
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S368 Q S K A G Y S S G S H Q Y P S
Rat Rattus norvegicus P35465 544 60559 D215 L P V T P T R D V A T S P I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 T370 H D K I N Y S T S G Y Q Y P S
Chicken Gallus gallus XP_415031 787 88575 S436 Q S K V S Y S S S S Y Q Y P L
Frog Xenopus laevis NP_001082100 650 73749 K321 V K P K P P E K P H P T Q L A
Zebra Danio Brachydanio rerio NP_998127 711 78596 P371 P S P Y Q H P P S Q P S P P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 K310 H H H Q H L A K S A S R A S S
Honey Bee Apis mellifera XP_001122147 624 70155 S295 Q R P L S Q L S T H N V N K Y
Nematode Worm Caenorhab. elegans Q17850 572 63863 T243 A R T L S I Y T K P K E E E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 I539 E E Q P L P P I P P T K S K T
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 Q593 E Q A M A Q A Q A A M S G Q L
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 86.6 6.6 N.A. 53.3 73.3 0 20 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 20 N.A. 66.6 80 6.6 26.6 N.A. 33.3 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 20 7 0 14 0 7 20 0 0 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 14 7 0 0 0 0 7 0 0 0 0 7 7 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 34 0 0 0 7 7 0 0 7 0 0 % G
% His: 14 7 7 0 7 7 0 0 0 14 34 0 0 0 0 % H
% Ile: 0 0 0 7 0 7 0 7 0 0 0 0 0 7 0 % I
% Lys: 0 7 47 7 0 0 0 14 7 0 7 7 0 14 0 % K
% Leu: 7 0 0 14 7 7 7 0 0 0 0 0 0 7 14 % L
% Met: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 7 0 7 0 0 % N
% Pro: 7 7 20 7 14 14 14 7 14 14 14 0 14 54 0 % P
% Gln: 47 7 7 7 7 14 0 7 0 7 0 47 7 7 0 % Q
% Arg: 0 14 0 0 0 0 7 0 0 0 0 7 0 0 0 % R
% Ser: 0 47 0 14 20 0 47 47 54 40 7 20 7 7 54 % S
% Thr: 0 0 7 7 0 7 0 14 7 0 14 7 0 0 7 % T
% Val: 7 0 7 7 0 0 0 0 7 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 47 7 0 0 0 14 0 47 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _