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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 27.58
Human Site: S375 Identified Species: 43.33
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S375 S S S H Q Y P S G Y H K A T L
Chimpanzee Pan troglodytes XP_525261 777 87548 S433 S S S H Q Y P S G Y H K A T L
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S433 S S S H Q Y P S G Y H K A T L
Dog Lupus familis XP_542895 719 81009 S375 S S S H Q Y P S G Y H K A T L
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S375 S G S H Q Y P S G Y H K A S L
Rat Rattus norvegicus P35465 544 60559 S222 D V A T S P I S P T E N N T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 S377 T S G Y Q Y P S G Y H K A A P
Chicken Gallus gallus XP_415031 787 88575 L443 S S S Y Q Y P L V Y H K A S H
Frog Xenopus laevis NP_001082100 650 73749 A328 K P H P T Q L A P H S S D P Q
Zebra Danio Brachydanio rerio NP_998127 711 78596 Y378 P S Q P S P P Y T P A G A H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S317 K S A S R A S S S S G G A S S
Honey Bee Apis mellifera XP_001122147 624 70155 Y302 S T H N V N K Y S Q S A L S S
Nematode Worm Caenorhab. elegans Q17850 572 63863 E250 T K P K E E E E K I P D L S K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 T546 I P P T K S K T S P I I S T A
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 L600 Q A A M S G Q L S R A A S K R
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 13.3 N.A. 66.6 66.6 0 20 N.A. 20 6.6 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 20 N.A. 80 80 13.3 20 N.A. 40 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 20 0 0 7 0 7 0 0 14 14 60 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % D
% Glu: 0 0 0 0 7 7 7 7 0 0 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 7 0 0 7 0 0 40 0 7 14 0 0 0 % G
% His: 0 0 14 34 0 0 0 0 0 7 47 0 0 7 7 % H
% Ile: 7 0 0 0 0 0 7 0 0 7 7 7 0 0 0 % I
% Lys: 14 7 0 7 7 0 14 0 7 0 0 47 0 7 7 % K
% Leu: 0 0 0 0 0 0 7 14 0 0 0 0 14 0 34 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 0 0 7 7 0 0 % N
% Pro: 7 14 14 14 0 14 54 0 14 14 7 0 0 7 7 % P
% Gln: 7 0 7 0 47 7 7 0 0 7 0 0 0 0 7 % Q
% Arg: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 7 % R
% Ser: 47 54 40 7 20 7 7 54 27 7 14 7 14 34 14 % S
% Thr: 14 7 0 14 7 0 0 7 7 7 0 0 0 40 7 % T
% Val: 0 7 0 0 7 0 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 0 47 0 14 0 47 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _