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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK7
All Species:
27.58
Human Site:
S375
Identified Species:
43.33
UniProt:
Q9P286
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P286
NP_065074.1
719
80745
S375
S
S
S
H
Q
Y
P
S
G
Y
H
K
A
T
L
Chimpanzee
Pan troglodytes
XP_525261
777
87548
S433
S
S
S
H
Q
Y
P
S
G
Y
H
K
A
T
L
Rhesus Macaque
Macaca mulatta
XP_001113709
777
87522
S433
S
S
S
H
Q
Y
P
S
G
Y
H
K
A
T
L
Dog
Lupus familis
XP_542895
719
81009
S375
S
S
S
H
Q
Y
P
S
G
Y
H
K
A
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C015
719
80930
S375
S
G
S
H
Q
Y
P
S
G
Y
H
K
A
S
L
Rat
Rattus norvegicus
P35465
544
60559
S222
D
V
A
T
S
P
I
S
P
T
E
N
N
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
S377
T
S
G
Y
Q
Y
P
S
G
Y
H
K
A
A
P
Chicken
Gallus gallus
XP_415031
787
88575
L443
S
S
S
Y
Q
Y
P
L
V
Y
H
K
A
S
H
Frog
Xenopus laevis
NP_001082100
650
73749
A328
K
P
H
P
T
Q
L
A
P
H
S
S
D
P
Q
Zebra Danio
Brachydanio rerio
NP_998127
711
78596
Y378
P
S
Q
P
S
P
P
Y
T
P
A
G
A
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
S317
K
S
A
S
R
A
S
S
S
S
G
G
A
S
S
Honey Bee
Apis mellifera
XP_001122147
624
70155
Y302
S
T
H
N
V
N
K
Y
S
Q
S
A
L
S
S
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
E250
T
K
P
K
E
E
E
E
K
I
P
D
L
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
T546
I
P
P
T
K
S
K
T
S
P
I
I
S
T
A
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
L600
Q
A
A
M
S
G
Q
L
S
R
A
A
S
K
R
Conservation
Percent
Protein Identity:
100
92.2
91.8
96.9
N.A.
93.8
31.2
N.A.
85.8
75.7
53.1
64.9
N.A.
45.6
45.4
31.1
N.A.
Protein Similarity:
100
92.4
92.2
98.3
N.A.
96.8
48.6
N.A.
92.5
82
64.8
75
N.A.
58.2
61
47
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
66.6
66.6
0
20
N.A.
20
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
20
N.A.
80
80
13.3
20
N.A.
40
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
27.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
20
0
0
7
0
7
0
0
14
14
60
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% D
% Glu:
0
0
0
0
7
7
7
7
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
7
0
0
40
0
7
14
0
0
0
% G
% His:
0
0
14
34
0
0
0
0
0
7
47
0
0
7
7
% H
% Ile:
7
0
0
0
0
0
7
0
0
7
7
7
0
0
0
% I
% Lys:
14
7
0
7
7
0
14
0
7
0
0
47
0
7
7
% K
% Leu:
0
0
0
0
0
0
7
14
0
0
0
0
14
0
34
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
7
0
0
0
0
0
7
7
0
0
% N
% Pro:
7
14
14
14
0
14
54
0
14
14
7
0
0
7
7
% P
% Gln:
7
0
7
0
47
7
7
0
0
7
0
0
0
0
7
% Q
% Arg:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
7
% R
% Ser:
47
54
40
7
20
7
7
54
27
7
14
7
14
34
14
% S
% Thr:
14
7
0
14
7
0
0
7
7
7
0
0
0
40
7
% T
% Val:
0
7
0
0
7
0
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
0
47
0
14
0
47
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _