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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 23.64
Human Site: S403 Identified Species: 37.14
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S403 S T A S Y L S S L S L S S S T
Chimpanzee Pan troglodytes XP_525261 777 87548 S461 S T A S Y L S S L S L S S S T
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S461 S T A S Y L S S L S L S S S T
Dog Lupus familis XP_542895 719 81009 S403 S T A S Y L S S L S I S S S T
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S403 S T A S Y L S S L S I S S S T
Rat Rattus norvegicus P35465 544 60559 E250 K K P K M S D E E I L E K L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 S405 I S T A S Y P S S P S I S S S
Chicken Gallus gallus XP_415031 787 88575 S471 S T A S Y P S S P S I T S S A
Frog Xenopus laevis NP_001082100 650 73749 Q356 R S P Q R E P Q R V S H E Q F
Zebra Danio Brachydanio rerio NP_998127 711 78596 P406 P P G A Y P P P S W G S P A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 R345 G Q P K Q D Q R L T H E Q F R
Honey Bee Apis mellifera XP_001122147 624 70155 L330 K Q T A E Q R L T H E Q F R A
Nematode Worm Caenorhab. elegans Q17850 572 63863 V278 K K M T D A E V L T K L R T I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 P574 A Q E T V T T P T S K P A Q A
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 A628 R Q P D I N G A P R M P Q T Q
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 20 66.6 0 13.3 N.A. 6.6 0 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 40 80 6.6 26.6 N.A. 13.3 6.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 40 20 0 7 0 7 0 0 0 0 7 7 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 7 7 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 0 7 7 7 7 7 0 7 14 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 7 % F
% Gly: 7 0 7 0 0 0 7 0 0 0 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 7 7 0 0 0 % H
% Ile: 7 0 0 0 7 0 0 0 0 7 20 7 0 0 7 % I
% Lys: 20 14 0 14 0 0 0 0 0 0 14 0 7 0 0 % K
% Leu: 0 0 0 0 0 34 0 7 47 0 27 7 0 7 0 % L
% Met: 0 0 7 0 7 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 7 27 0 0 14 20 14 14 7 0 14 7 0 0 % P
% Gln: 0 27 0 7 7 7 7 7 0 0 0 7 14 14 7 % Q
% Arg: 14 0 0 0 7 0 7 7 7 7 0 0 7 7 14 % R
% Ser: 40 14 0 40 7 7 40 47 14 47 14 40 47 47 7 % S
% Thr: 0 40 14 14 0 7 7 0 14 14 0 7 0 14 34 % T
% Val: 0 0 0 0 7 0 0 7 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 47 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _