KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK7
All Species:
24.85
Human Site:
S405
Identified Species:
39.05
UniProt:
Q9P286
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P286
NP_065074.1
719
80745
S405
A
S
Y
L
S
S
L
S
L
S
S
S
T
Y
P
Chimpanzee
Pan troglodytes
XP_525261
777
87548
S463
A
S
Y
L
S
S
L
S
L
S
S
S
T
Y
P
Rhesus Macaque
Macaca mulatta
XP_001113709
777
87522
S463
A
S
Y
L
S
S
L
S
L
S
S
S
T
Y
P
Dog
Lupus familis
XP_542895
719
81009
S405
A
S
Y
L
S
S
L
S
I
S
S
S
T
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C015
719
80930
S405
A
S
Y
L
S
S
L
S
I
S
S
S
T
Y
P
Rat
Rattus norvegicus
P35465
544
60559
I252
P
K
M
S
D
E
E
I
L
E
K
L
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
P407
T
A
S
Y
P
S
S
P
S
I
S
S
S
A
Y
Chicken
Gallus gallus
XP_415031
787
88575
S473
A
S
Y
P
S
S
P
S
I
T
S
S
A
Y
P
Frog
Xenopus laevis
NP_001082100
650
73749
V358
P
Q
R
E
P
Q
R
V
S
H
E
Q
F
R
A
Zebra Danio
Brachydanio rerio
NP_998127
711
78596
W408
G
A
Y
P
P
P
S
W
G
S
P
A
E
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
T347
P
K
Q
D
Q
R
L
T
H
E
Q
F
R
A
A
Honey Bee
Apis mellifera
XP_001122147
624
70155
H332
T
A
E
Q
R
L
T
H
E
Q
F
R
A
A
L
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
T280
M
T
D
A
E
V
L
T
K
L
R
T
I
V
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S576
E
T
V
T
T
P
T
S
K
P
A
Q
A
R
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
R630
P
D
I
N
G
A
P
R
M
P
Q
T
Q
G
A
Conservation
Percent
Protein Identity:
100
92.2
91.8
96.9
N.A.
93.8
31.2
N.A.
85.8
75.7
53.1
64.9
N.A.
45.6
45.4
31.1
N.A.
Protein Similarity:
100
92.4
92.2
98.3
N.A.
96.8
48.6
N.A.
92.5
82
64.8
75
N.A.
58.2
61
47
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
20
66.6
0
20
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
33.3
80
0
33.3
N.A.
13.3
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
27.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
20
0
7
0
7
0
0
0
0
7
7
20
20
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
7
7
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
7
7
7
7
7
0
7
14
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
7
7
0
0
% F
% Gly:
7
0
0
0
7
0
0
0
7
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
7
7
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
7
20
7
0
0
7
0
7
% I
% Lys:
0
14
0
0
0
0
0
0
14
0
7
0
0
0
0
% K
% Leu:
0
0
0
34
0
7
47
0
27
7
0
7
0
0
7
% L
% Met:
7
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
27
0
0
14
20
14
14
7
0
14
7
0
0
0
47
% P
% Gln:
0
7
7
7
7
7
0
0
0
7
14
14
7
7
0
% Q
% Arg:
0
0
7
0
7
7
7
7
0
0
7
7
14
14
0
% R
% Ser:
0
40
7
7
40
47
14
47
14
40
47
47
7
7
14
% S
% Thr:
14
14
0
7
7
0
14
14
0
7
0
14
34
0
0
% T
% Val:
0
0
7
0
0
7
0
7
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
7
0
0
0
0
0
0
0
0
0
40
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _