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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK7 All Species: 36.06
Human Site: S671 Identified Species: 56.67
UniProt: Q9P286 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P286 NP_065074.1 719 80745 S671 K D L H K V S S V L R G F L D
Chimpanzee Pan troglodytes XP_525261 777 87548 S729 K D L H K V S S V L R G F L D
Rhesus Macaque Macaca mulatta XP_001113709 777 87522 S729 K D L H K V S S V L R G F L D
Dog Lupus familis XP_542895 719 81009 S671 K D L H K V S S V L R G F L D
Cat Felis silvestris
Mouse Mus musculus Q8C015 719 80930 S671 K D L H K V S S M L R G F L D
Rat Rattus norvegicus P35465 544 60559 R499 I F R D F L N R C L E M D V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514843 722 81837 S674 K D L H K V S S V L R G F L D
Chicken Gallus gallus XP_415031 787 88575 S739 K D M H K V S S V L R G F L D
Frog Xenopus laevis NP_001082100 650 73749 K605 Q K V S P L L K G F L D R L L
Zebra Danio Brachydanio rerio NP_998127 711 78596 S663 K E S H K V S S V L R A F L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXE5 639 69601 S594 K V S P R L Q S F L D R M L V
Honey Bee Apis mellifera XP_001122147 624 70155 F579 V S P R L Q G F L E R M L V R
Nematode Worm Caenorhab. elegans Q17850 572 63863 L527 K D F V D S A L E V Q V E N R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03497 939 102344 S842 K E P E N L S S S L K K F L D
Red Bread Mold Neurospora crassa Q7RZD3 954 103773 P896 K D E Q S L S P V F R D F L Y
Conservation
Percent
Protein Identity: 100 92.2 91.8 96.9 N.A. 93.8 31.2 N.A. 85.8 75.7 53.1 64.9 N.A. 45.6 45.4 31.1 N.A.
Protein Similarity: 100 92.4 92.2 98.3 N.A. 96.8 48.6 N.A. 92.5 82 64.8 75 N.A. 58.2 61 47 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 6.6 N.A. 100 93.3 6.6 80 N.A. 26.6 6.6 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 100 100 26.6 86.6 N.A. 40 20 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27 27.7
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 42.6
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 60 0 7 7 0 0 0 0 0 7 14 7 0 60 % D
% Glu: 0 14 7 7 0 0 0 0 7 7 7 0 7 0 7 % E
% Phe: 0 7 7 0 7 0 0 7 7 14 0 0 67 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 7 0 0 47 0 0 0 % G
% His: 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 80 7 0 0 54 0 0 7 0 0 7 7 0 0 0 % K
% Leu: 0 0 40 0 7 34 7 7 7 74 7 0 7 80 7 % L
% Met: 0 0 7 0 0 0 0 0 7 0 0 14 7 0 0 % M
% Asn: 0 0 0 0 7 0 7 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 14 7 7 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 7 0 7 7 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 7 7 7 0 0 7 0 0 67 7 7 0 14 % R
% Ser: 0 7 14 7 7 7 67 67 7 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 7 7 7 0 54 0 0 54 7 0 7 0 14 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _