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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK7
All Species:
23.33
Human Site:
T397
Identified Species:
36.67
UniProt:
Q9P286
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P286
NP_065074.1
719
80745
T397
S
S
S
Q
Y
I
S
T
A
S
Y
L
S
S
L
Chimpanzee
Pan troglodytes
XP_525261
777
87548
T455
S
S
S
Q
Y
I
S
T
A
S
Y
L
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001113709
777
87522
T455
S
S
S
Q
Y
I
S
T
A
S
Y
L
S
S
L
Dog
Lupus familis
XP_542895
719
81009
T397
T
S
S
Q
Y
I
S
T
A
S
Y
L
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C015
719
80930
T397
T
S
S
Q
Y
I
S
T
A
S
Y
L
S
S
L
Rat
Rattus norvegicus
P35465
544
60559
K244
N
T
E
K
Q
K
K
K
P
K
M
S
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514843
722
81837
S399
Q
S
S
S
Q
Y
I
S
T
A
S
Y
P
S
S
Chicken
Gallus gallus
XP_415031
787
88575
T465
P
S
S
P
Y
I
S
T
A
S
Y
P
S
S
P
Frog
Xenopus laevis
NP_001082100
650
73749
S350
Q
H
P
A
Q
P
R
S
P
Q
R
E
P
Q
R
Zebra Danio
Brachydanio rerio
NP_998127
711
78596
P400
P
S
S
P
Y
V
P
P
G
A
Y
P
P
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
Q339
A
S
G
G
A
A
G
Q
P
K
Q
D
Q
R
L
Honey Bee
Apis mellifera
XP_001122147
624
70155
Q324
S
S
N
T
T
N
K
Q
T
A
E
Q
R
L
T
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
K272
R
G
Q
K
A
K
K
K
M
T
D
A
E
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
Q568
Q
S
P
K
A
P
A
Q
E
T
V
T
T
P
T
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
Q622
S
Q
H
Q
H
P
R
Q
P
D
I
N
G
A
P
Conservation
Percent
Protein Identity:
100
92.2
91.8
96.9
N.A.
93.8
31.2
N.A.
85.8
75.7
53.1
64.9
N.A.
45.6
45.4
31.1
N.A.
Protein Similarity:
100
92.4
92.2
98.3
N.A.
96.8
48.6
N.A.
92.5
82
64.8
75
N.A.
58.2
61
47
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
20
73.3
0
26.6
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
33.3
73.3
6.6
40
N.A.
20
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
27.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
20
7
7
0
40
20
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
7
7
7
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
7
0
7
7
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
7
0
0
7
0
7
0
0
0
7
0
0
% G
% His:
0
7
7
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
40
7
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
20
0
14
20
14
0
14
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
34
0
7
47
% L
% Met:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% M
% Asn:
7
0
7
0
0
7
0
0
0
0
0
7
0
0
0
% N
% Pro:
14
0
14
14
0
20
7
7
27
0
0
14
20
14
14
% P
% Gln:
20
7
7
40
20
0
0
27
0
7
7
7
7
7
0
% Q
% Arg:
7
0
0
0
0
0
14
0
0
0
7
0
7
7
7
% R
% Ser:
34
74
54
7
0
0
40
14
0
40
7
7
40
47
14
% S
% Thr:
14
7
0
7
7
0
0
40
14
14
0
7
7
0
14
% T
% Val:
0
0
0
0
0
7
0
0
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
47
7
0
0
0
0
47
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _